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NBDY negative regulator of P-body association [ Homo sapiens (human) ]

Gene ID: 550643, updated on 6-Sep-2022

Summary

Official Symbol
NBDYprovided by HGNC
Official Full Name
negative regulator of P-body associationprovided by HGNC
Primary source
HGNC:HGNC:50713
See related
Ensembl:ENSG00000204272 MIM:300992; AllianceGenome:HGNC:50713
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NoBody; LINC01420
Summary
Involved in negative regulation of cytoplasmic mRNA processing body assembly and nuclear-transcribed mRNA catabolic process. Located in P-body. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thyroid (RPKM 34.2), adrenal (RPKM 31.8) and 25 other tissues See more
Orthologs
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Genomic context

See NBDY in Genome Data Viewer
Location:
Xp11.21
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (56729243..56819179)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (56022640..56117983)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (56755676..56845612)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ubiquilin 2 Neighboring gene uncharacterized LOC124905194 Neighboring gene ubiquinol-cytochrome c reductase binding protein pseudogene 1 Neighboring gene spindlin family member 3 Neighboring gene SPIN2 family pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association study identifies loci affecting blood copper, selenium and zinc.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in P-body IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
negative regulator of P-body association
Names
P-body dissociating protein
long intergenic non-protein coding RNA 1420
non-annotated P-body dissociating polypeptide
protein NoBody

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001348129.2NP_001335058.1  negative regulator of P-body association

    Status: VALIDATED

    Source sequence(s)
    AA131515, AL158200, AL354865, BC048131, BX537532, CA444043
    Consensus CDS
    CCDS87751.1
    UniProtKB/Swiss-Prot
    A0A0U1RRE5
    UniProtKB/TrEMBL
    A0A4P8PLQ7
    Related
    ENSP00000489583.1, ENST00000374922.9
    Conserved Domains (1) summary
    cd20243
    Location:168
    NoBody; Negative regulator of P-body association

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    56729243..56819179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    56022640..56117983
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)