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SUSD4 sushi domain containing 4 [ Homo sapiens (human) ]

Gene ID: 55061, updated on 6-Aug-2017
Official Symbol
SUSD4provided by HGNC
Official Full Name
sushi domain containing 4provided by HGNC
Primary source
HGNC:HGNC:25470
See related
Ensembl:ENSG00000143502 MIM:615827; Vega:OTTHUMG00000037936
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRO222
Orthologs
Location:
1q41
Exon count:
13
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 1 NC_000001.11 (223220819..223364240, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (223394161..223537564, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985323 Neighboring gene toll like receptor 5 Neighboring gene uncharacterized LOC105373025 Neighboring gene RNA, U4 small nuclear 57, pseudogene Neighboring gene coiled-coil domain containing 185

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ10052

Gene Ontology Provided by GOA

Process Evidence Code Pubs
complement activation, classical pathway IEA
Inferred from Electronic Annotation
more info
 
innate immune response IEA
Inferred from Electronic Annotation
more info
 
regulation of complement activation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
sushi domain-containing protein 4
Names
YHGM196
testicular secretory protein Li 55

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037175.2NP_001032252.1  sushi domain-containing protein 4 isoform b precursor

    See identical proteins and their annotated locations for NP_001032252.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding region compared to variant 1. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a.
    Source sequence(s)
    BC004888, DA125047
    Consensus CDS
    CCDS31034.1
    UniProtKB/Swiss-Prot
    Q5VX71
    UniProtKB/TrEMBL
    A0A140VK55
    Related
    ENSP00000339926.6, OTTHUMP00000036038, ENST00000344029.6, OTTHUMT00000092595
    Conserved Domains (2) summary
    cd00033
    Location:180237
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:125177
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
  2. NM_017982.3NP_060452.3  sushi domain-containing protein 4 isoform a precursor

    See identical proteins and their annotated locations for NP_060452.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AK096265, AY358495, BF446433, DA125047
    Consensus CDS
    CCDS41471.1
    UniProtKB/Swiss-Prot
    Q5VX71
    UniProtKB/TrEMBL
    B3KTY0
    Related
    ENSP00000355843.4, ENST00000366878.8
    Conserved Domains (3) summary
    cd00033
    Location:180237
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:243297
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:54296
    PHA02927; secreted complement-binding protein; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p7 Primary Assembly

    Range
    223220819..223364240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001583.1XP_016857072.1  sushi domain-containing protein 4 isoform X1

  2. XM_017001584.1XP_016857073.1  sushi domain-containing protein 4 isoform X2

  3. XM_006711408.1XP_006711471.1  sushi domain-containing protein 4 isoform X4

    See identical proteins and their annotated locations for XP_006711471.1

    Related
    ENSP00000477432.1, OTTHUMP00000274359, ENST00000608996.5, OTTHUMT00000472744
    Conserved Domains (3) summary
    cd00033
    Location:180237
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:245299
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:54298
    PHA02927; secreted complement-binding protein; Provisional
  4. XM_005273172.1XP_005273229.1  sushi domain-containing protein 4 isoform X8

    See identical proteins and their annotated locations for XP_005273229.1

    UniProtKB/TrEMBL
    B7Z469
    Conserved Domains (2) summary
    cd00033
    Location:2077
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:83137
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
  5. XM_011509687.1XP_011507989.1  sushi domain-containing protein 4 isoform X7

    Conserved Domains (2) summary
    cd00033
    Location:2077
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:85139
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
  6. XM_017001587.1XP_016857076.1  sushi domain-containing protein 4 isoform X5

    UniProtKB/Swiss-Prot
    Q5VX71
    Conserved Domains (3) summary
    cd00033
    Location:180237
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:243297
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:54296
    PHA02927; secreted complement-binding protein; Provisional
  7. XM_005273169.1XP_005273226.1  sushi domain-containing protein 4 isoform X4

    See identical proteins and their annotated locations for XP_005273226.1

    Conserved Domains (3) summary
    cd00033
    Location:180237
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:245299
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:54298
    PHA02927; secreted complement-binding protein; Provisional
  8. XM_017001585.1XP_016857074.1  sushi domain-containing protein 4 isoform X3

  9. XM_017001588.1XP_016857077.1  sushi domain-containing protein 4 isoform X5

    UniProtKB/Swiss-Prot
    Q5VX71
    Related
    ENSP00000344219.3, OTTHUMP00000036037, ENST00000343846.7, OTTHUMT00000092592
    Conserved Domains (3) summary
    cd00033
    Location:180237
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:243297
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:54296
    PHA02927; secreted complement-binding protein; Provisional
  10. XM_011509685.1XP_011507987.1  sushi domain-containing protein 4 isoform X4

    See identical proteins and their annotated locations for XP_011507987.1

    Conserved Domains (3) summary
    cd00033
    Location:180237
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:245299
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:54298
    PHA02927; secreted complement-binding protein; Provisional
  11. XM_017001586.1XP_016857075.1  sushi domain-containing protein 4 isoform X3

  12. XM_017001589.1XP_016857078.1  sushi domain-containing protein 4 isoform X6

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    224667308..224810684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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