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pecr peroxisomal trans-2-enoyl-CoA reductase [ Danio rerio (zebrafish) ]

Gene ID: 550422, updated on 12-Nov-2022

Summary

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Official Symbol
pecrprovided by ZNC
Official Full Name
peroxisomal trans-2-enoyl-CoA reductaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-232
See related
Ensembl:ENSDARG00000055976 AllianceGenome:ZFIN:ZDB-GENE-050417-232
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:112155
Summary
Predicted to enable trans-2-enoyl-CoA reductase (NADPH) activity. Predicted to be involved in phytol metabolic process. Predicted to be active in peroxisome. Orthologous to human PECR (peroxisomal trans-2-enoyl-CoA reductase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See pecr in Genome Data Viewer
Location:
chromosome: 11
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (30355441..30364847, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (30107984..30117663, complement)
103 previous assembly Zv9 (GCF_000002035.4) 11 NC_007122.5 (31230788..31240348, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene CASP8 and FADD-like apoptosis regulator a Neighboring gene transmembrane protein 169a Neighboring gene mitogen-activated protein kinase kinase kinase kinase 3a Neighboring gene transmembrane protein 178a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Insights Into the Peroxisomal Protein Inventory of Zebrafish. Kamoshita M, et al. Front Physiol, 2022. PMID 35295584, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables trans-2-enoyl-CoA reductase (NADPH) activity IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Process Evidence Code Pubs
involved_in phytol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 

General protein information

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Preferred Names
peroxisomal trans-2-enoyl-CoA reductase
NP_001017727.1
XP_005169421.1
XP_005169422.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017727.1 → NP_001017727.1  peroxisomal trans-2-enoyl-CoA reductase

    See identical proteins and their annotated locations for NP_001017727.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093230
    UniProtKB/TrEMBL
    A0A8M1N5A0, Q567C7
    Related
    ENSDARP00000072849.2, ENSDART00000078387.4
    Conserved Domains (2) summary
    cd05369
    Location:28 → 263
    TER_DECR_SDR_a; Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR
    PRK05653
    Location:28 → 263
    fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Validated

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    30355441..30364847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169365.4 → XP_005169422.1  peroxisomal trans-2-enoyl-CoA reductase isoform X2

    UniProtKB/TrEMBL
    A0A8M2BGN1
    Conserved Domains (1) summary
    cl21454
    Location:12 → 139
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_005169364.4 → XP_005169421.1  peroxisomal trans-2-enoyl-CoA reductase isoform X1

    UniProtKB/TrEMBL
    A0A8M2BGN0
    Conserved Domains (1) summary
    cl21454
    Location:1 → 177
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein Strain
Heading Accession and Version

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