Format

Send to:

Choose Destination

C17orf80 chromosome 17 open reading frame 80 [ Homo sapiens (human) ]

Gene ID: 55028, updated on 1-Jun-2020

Summary

Official Symbol
C17orf80provided by HGNC
Official Full Name
chromosome 17 open reading frame 80provided by HGNC
Primary source
HGNC:HGNC:29601
See related
Ensembl:ENSG00000141219
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIG3; HLC-8; SPEP1
Expression
Ubiquitous expression in testis (RPKM 11.0), thyroid (RPKM 5.9) and 25 other tissues See more
Orthologs

Genomic context

See C17orf80 in Genome Data Viewer
Location:
17q25.1
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (73232433..73248959)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (71228372..71245098)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene somatostatin receptor 2 Neighboring gene family with sequence similarity 104 member A Neighboring gene component of oligomeric golgi complex 1 Neighboring gene cleavage and polyadenylation specific factor 4 like Neighboring gene Sharpr-MPRA regulatory region 4436 Neighboring gene CDC42 effector protein 4 Neighboring gene sidekick cell adhesion molecule 2 Neighboring gene uncharacterized LOC101928251

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20721

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein C17orf80
Names
cell migration-inducing gene 3 protein
human lung cancer oncogene 8 protein
lung cancer-related protein 8
sperm-expressed protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054938.1 RefSeqGene

    Range
    5533..21870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001100621.3NP_001094091.2  uncharacterized protein C17orf80 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. Variants 2 and 4 encode the same isoform (b), which is shorter than isoform a.
    Source sequence(s)
    AC087301, AC097641
    Consensus CDS
    CCDS42377.1
    Related
    ENSP00000268942.8, ENST00000268942.12
  2. NM_001100622.4NP_001094092.2  uncharacterized protein C17orf80 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform c, which is shorter and has a distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AC087301, AC097641
    Consensus CDS
    CCDS45767.1
    Related
    ENSP00000396970.2, ENST00000426147.6
  3. NM_001288770.3NP_001275699.2  uncharacterized protein C17orf80 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. Variants 2, 4 and 8 encode the same isoform (b), which is shorter than isoform a.
    Source sequence(s)
    AC087301, AC097641
    Consensus CDS
    CCDS42377.1
    Related
    ENSP00000464132.1, ENST00000577615.5
  4. NM_001288771.3NP_001275700.2  uncharacterized protein C17orf80 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, lacks an alternate exon in the 3' coding region and contains an alternate 3' terminal exon, compared to variant 1. It encodes isoform d, which is shorter and has a distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AC087301, AC097641
    Consensus CDS
    CCDS74145.1
    Related
    ENSP00000255557.4, ENST00000255557.8
  5. NM_001351264.2NP_001338193.2  uncharacterized protein C17orf80 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Both variants 1 and 7 encode the same isoform (a).
    Source sequence(s)
    AC087301, AC097641
    Consensus CDS
    CCDS11694.1
  6. NM_001351265.2NP_001338194.2  uncharacterized protein C17orf80 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and lacks an alternate in-frame exon in the 3' coding region compared to variant 1. Variants 2, 4 and 8 encode the same isoform (b), which is shorter than isoform a.
    Source sequence(s)
    AC087301, AC097641
    Consensus CDS
    CCDS42377.1
  7. NM_017941.5NP_060411.2  uncharacterized protein C17orf80 isoform a

    See identical proteins and their annotated locations for NP_060411.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AY163812, AY239293, BC005005, BU736238, BU788930, DC372573, DT220543
    Consensus CDS
    CCDS11694.1
    UniProtKB/Swiss-Prot
    Q9BSJ5
    UniProtKB/TrEMBL
    A0A024R8P4
    Related
    ENSP00000351937.2, ENST00000359042.6

RNA

  1. NR_110105.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AY163812, AY239293, BG754800, BU736238, BU788930, DT220543

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    73232433..73248959
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011524961.1XP_011523263.1  uncharacterized protein C17orf80 isoform X1

    See identical proteins and their annotated locations for XP_011523263.1

    UniProtKB/Swiss-Prot
    Q9BSJ5
    Related
    ENSP00000440551.2, ENST00000535032.6
  2. XM_006721966.4XP_006722029.1  uncharacterized protein C17orf80 isoform X2

    UniProtKB/TrEMBL
    I3L072
  3. XM_011524962.2XP_011523264.1  uncharacterized protein C17orf80 isoform X1

    See identical proteins and their annotated locations for XP_011523264.1

    UniProtKB/Swiss-Prot
    Q9BSJ5
Support Center