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TMEM255A transmembrane protein 255A [ Homo sapiens (human) ]

Gene ID: 55026, updated on 1-Aug-2020

Summary

Official Symbol
TMEM255Aprovided by HGNC
Official Full Name
transmembrane protein 255Aprovided by HGNC
Primary source
HGNC:HGNC:26086
See related
Ensembl:ENSG00000125355
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM70A
Expression
Broad expression in ovary (RPKM 8.6), brain (RPKM 2.6) and 15 other tissues See more
Orthologs

Genomic context

See TMEM255A in Genome Data Viewer
Location:
Xq24
Exon count:
11
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (120250984..120311536, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (119392505..119445391, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 30 Neighboring gene NFKB activating protein pseudogene 1 Neighboring gene prefoldin subunit 4-like Neighboring gene zinc finger and BTB domain containing 33 Neighboring gene ATPase Na+/K+ transporting family member beta 4 Neighboring gene lysosomal associated membrane protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20716

Gene Ontology Provided by GOA

Process Evidence Code Pubs
response to bacterium IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 255A
Names
family with sequence similarity 70, member A
protein FAM70A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104544.3NP_001098014.1  transmembrane protein 255A isoform 2

    See identical proteins and their annotated locations for NP_001098014.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AC002086, AL512286
    Consensus CDS
    CCDS43986.1
    UniProtKB/Swiss-Prot
    Q5JRV8
    UniProtKB/TrEMBL
    Q7Z4S8
    Related
    ENSP00000360420.4, ENST00000371369.8
    Conserved Domains (1) summary
    pfam14967
    Location:9324
    FAM70; FAM70 protein
  2. NM_001104545.1NP_001098015.1  transmembrane protein 255A isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks three alternate in-frame exons in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform 3), compared to isoform 1.
    Source sequence(s)
    AF450484, BC047054, DA758358, DB165640
    Consensus CDS
    CCDS48157.1
    UniProtKB/Swiss-Prot
    Q5JRV8
    UniProtKB/TrEMBL
    Q7Z4S8
    Related
    ENSP00000405781.1, ENST00000440464.5
    Conserved Domains (1) summary
    pfam14967
    Location:9240
    FAM70; FAM70 protein
  3. NM_017938.3NP_060408.3  transmembrane protein 255A isoform 1

    See identical proteins and their annotated locations for NP_060408.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AF450484, BC047054, DA758358
    Consensus CDS
    CCDS14597.1
    UniProtKB/Swiss-Prot
    Q5JRV8
    UniProtKB/TrEMBL
    Q7Z4S8
    Related
    ENSP00000310110.5, ENST00000309720.9
    Conserved Domains (1) summary
    pfam14967
    Location:9348
    FAM70; FAM70 protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    120250984..120311536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017029619.2XP_016885108.1  transmembrane protein 255A isoform X1

RNA

  1. XR_001755706.2 RNA Sequence

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