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PRPF39 pre-mRNA processing factor 39 [ Homo sapiens (human) ]

Gene ID: 55015, updated on 13-Mar-2020

Summary

Official Symbol
PRPF39provided by HGNC
Official Full Name
pre-mRNA processing factor 39provided by HGNC
Primary source
HGNC:HGNC:20314
See related
Ensembl:ENSG00000185246 MIM:614907
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in skin (RPKM 15.3), prostate (RPKM 14.2) and 25 other tissues See more
Orthologs

Genomic context

See PRPF39 in Genome Data Viewer
Location:
14q21.2
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (45084116..45116282)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (45553302..45584804)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene TOG array regulator of axonemal microtubules 1 Neighboring gene uncharacterized LOC105370474 Neighboring gene small nucleolar RNA, C/D box 127 Neighboring gene FKBP prolyl isomerase 3 Neighboring gene FA complementation group M Neighboring gene MIS18 binding protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11128, FLJ20666, FLJ45460, MGC149842, MGC149843

Gene Ontology Provided by GOA

Process Evidence Code Pubs
mRNA 5'-splice site recognition IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
U1 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
commitment complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
pre-mRNA-processing factor 39
Names
PRP39 homolog
PRP39 pre-mRNA processing factor 39 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017922.4NP_060392.3  pre-mRNA-processing factor 39

    See identical proteins and their annotated locations for NP_060392.3

    Status: VALIDATED

    Source sequence(s)
    AL121809, BC051886, BC125126, DB339898, DC306976
    Consensus CDS
    CCDS9682.2
    UniProtKB/Swiss-Prot
    Q86UA1
    Related
    ENSP00000348010.6, ENST00000355765.11
    Conserved Domains (4) summary
    smart00386
    Location:367399
    HAT; HAT (Half-A-TPR) repeats
    COG5107
    Location:50455
    RNA14; Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and modification]
    sd00006
    Location:455483
    TPR; TPR repeat [structural motif]
    pfam13432
    Location:459523
    TPR_16; Tetratricopeptide repeat

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    45084116..45116282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_018333.1: Suppressed sequence

    Description
    NM_018333.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript, and the CDS is partial.
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