Format

Send to:

Choose Destination

AURKAIP1 aurora kinase A interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 54998, updated on 7-Jun-2020

Summary

Official Symbol
AURKAIP1provided by HGNC
Official Full Name
aurora kinase A interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:24114
See related
Ensembl:ENSG00000175756 MIM:609183
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AIP; AKIP; MRP-S38
Expression
Ubiquitous expression in testis (RPKM 40.0), kidney (RPKM 27.3) and 25 other tissues See more
Orthologs

Genomic context

See AURKAIP1 in Genome Data Viewer
Location:
1p36.33
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (1373730..1375516, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (1309110..1310818, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene dishevelled segment polarity protein 1 Neighboring gene microRNA 6808 Neighboring gene matrix remodeling associated 8 Neighboring gene NADH:ubiquinone oxidoreductase subunit B4 pseudogene 8 Neighboring gene cyclin L2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20608

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
mRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial translational elongation TAS
Traceable Author Statement
more info
 
mitochondrial translational termination TAS
Traceable Author Statement
more info
 
negative regulation of mitotic nuclear division NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of proteolysis IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
mitochondrial inner membrane TAS
Traceable Author Statement
more info
 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
aurora kinase A-interacting protein
Names
28S ribosomal protein S38, mitochondrial
AURKA-interacting protein
aurora-A kinase interacting protein
mitochondrial small ribosomal subunit protein mS38

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127229.2NP_001120701.1  aurora kinase A-interacting protein

    See identical proteins and their annotated locations for NP_001120701.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has a 5'UTR resulting from use of an alternate splice donor site.
    Source sequence(s)
    AK000615, AL139287, AW576100, BM781908, F31434
    Consensus CDS
    CCDS25.1
    UniProtKB/Swiss-Prot
    Q9NWT8
    UniProtKB/TrEMBL
    A0A024R0F0
    Related
    ENSP00000368130.3, ENST00000378853.3
    Conserved Domains (1) summary
    pfam08213
    Location:127157
    DUF1713; Mitochondrial domain of unknown function (DUF1713)
  2. NM_001127230.2NP_001120702.1  aurora kinase A-interacting protein

    See identical proteins and their annotated locations for NP_001120702.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has a 5'UTR resulting from use of an alternate splice donor site.
    Source sequence(s)
    AL139287, BC022808, BC062333, BE903314, BP198074, DN994953
    Consensus CDS
    CCDS25.1
    UniProtKB/Swiss-Prot
    Q9NWT8
    UniProtKB/TrEMBL
    A0A024R0F0
    Related
    ENSP00000319778.5, ENST00000321751.9
    Conserved Domains (1) summary
    pfam08213
    Location:127157
    DUF1713; Mitochondrial domain of unknown function (DUF1713)
  3. NM_017900.3NP_060370.1  aurora kinase A-interacting protein

    See identical proteins and their annotated locations for NP_060370.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) has a 5'UTR resulting from use of an alternate splice donor site.
    Source sequence(s)
    BC062333, BG764236
    Consensus CDS
    CCDS25.1
    UniProtKB/Swiss-Prot
    Q9NWT8
    UniProtKB/TrEMBL
    A0A024R0F0
    Related
    ENSP00000340656.5, ENST00000338338.9
    Conserved Domains (1) summary
    pfam08213
    Location:127157
    DUF1713; Mitochondrial domain of unknown function (DUF1713)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    1373730..1375516 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024447924.1XP_024303692.1  aurora kinase A-interacting protein isoform X2

    Conserved Domains (1) summary
    pfam08213
    Location:186216
    DUF1713; Mitochondrial domain of unknown function (DUF1713)
  2. XM_011541670.3XP_011539972.1  aurora kinase A-interacting protein isoform X1

    Conserved Domains (1) summary
    pfam08213
    Location:156186
    DUF1713; Mitochondrial domain of unknown function (DUF1713)
Support Center