dolpp1 dolichyldiphosphatase 1 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: dolpp1provided by Xenbase
Official Full Name: dolichyldiphosphatase 1provided by Xenbase
Primary source: Xenbase:XB-GENE-996706
See related: Ensembl:ENSXETG00000018964 AllianceGenome:Xenbase:XB-GENE-996706
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: lsfr2
Summary: Predicted to enable dolichyldiphosphatase activity. Predicted to be involved in protein N-linked glycosylation. Predicted to act upstream of or within protein glycosylation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human DOLPP1 (dolichyldiphosphatase 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	8	NC_030684.2 (21682410..21690939)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	8	NC_030684.1 (5190562..5198964, complement)

Chromosome 8 - NC_030684.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables dolichyldiphosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables dolichyldiphosphatase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein N-linked glycosylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dolichyldiphosphatase 1

Names: dolichyl pyrophosphate phosphatase 1

NP_001017014.1

EC 3.6.1.43

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017014.2 → NP_001017014.1 dolichyldiphosphatase 1

See identical proteins and their annotated locations for NP_001017014.1

Status: PROVISIONAL

Source sequence(s)

CR762228

UniProtKB/TrEMBL

F6WAU5, F7ADQ4, Q28F14

Related

ENSXETP00000041134.3, ENSXETT00000041134.4

Conserved Domains (1) summary

cd03382
Location:16 → 180

PAP2_dolichyldiphosphatase; PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is ...