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TMEM160 transmembrane protein 160 [ Homo sapiens (human) ]

Gene ID: 54958, updated on 22-Sep-2022

Summary

Official Symbol
TMEM160provided by HGNC
Official Full Name
transmembrane protein 160provided by HGNC
Primary source
HGNC:HGNC:26042
See related
Ensembl:ENSG00000130748 AllianceGenome:HGNC:26042
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in kidney (RPKM 4.9), brain (RPKM 4.2) and 19 other tissues See more
Orthologs
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Genomic context

See TMEM160 in Genome Data Viewer
Location:
19q13.32
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (47045909..47048624, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (49871218..49873934, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (47549167..47551882, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene Rho GTPase activating protein 35 Neighboring gene neuronal PAS domain protein 1 Neighboring gene Sharpr-MPRA regulatory region 8906 Neighboring gene zinc finger CCCH-type containing 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
EBI GWAS Catalog
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
EBI GWAS Catalog

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vpr vpr HIV-1 Vpr is identified to have a physical interaction with transmembrane protein 160 (TMEM160) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ20512

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017854.2NP_060324.1  transmembrane protein 160 precursor

    See identical proteins and their annotated locations for NP_060324.1

    Status: VALIDATED

    Source sequence(s)
    AK000519
    Consensus CDS
    CCDS12695.1
    UniProtKB/Swiss-Prot
    Q9BU41, Q9NX00
    Related
    ENSP00000253047.5, ENST00000253047.7

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    47045909..47048624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    49871218..49873934 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)