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ODR4 odr-4 GPCR localization factor homolog [ Homo sapiens (human) ]

Gene ID: 54953, updated on 13-Mar-2020

Summary

Official Symbol
ODR4provided by HGNC
Official Full Name
odr-4 GPCR localization factor homologprovided by HGNC
Primary source
HGNC:HGNC:24299
See related
Ensembl:ENSG00000157181 MIM:609335
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TTG1; odr-4; C1orf27
Expression
Ubiquitous expression in thyroid (RPKM 12.6), prostate (RPKM 9.5) and 25 other tissues See more
Orthologs

Genomic context

See ODR4 in Genome Data Viewer
Location:
1q31.1
Exon count:
15
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (186375758..186421375)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (186344890..186390503)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene hemicentin 1 Neighboring gene uncharacterized LOC105371654 Neighboring gene RNA, U6 small nuclear 1240, pseudogene Neighboring gene proteoglycan 4 Neighboring gene translocated promoter region, nuclear basket protein Neighboring gene PDC antisense RNA 1 Neighboring gene phosducin Neighboring gene parkin coregulated like pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20505

Gene Ontology Provided by GOA

Process Evidence Code Pubs
protein localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein odr-4 homolog
Names
LAG1-interacting protein
odorant response abnormal 4
transactivated by recombinant transforming growth factor beta
transactivated by recombinant transforming growth factor beta 1
transactivated by transforming growth factor beta protein 1
NP_001157717.1
NP_001157718.1
NP_060317.3
XP_011507962.1
XP_011507963.1
XP_016857032.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164245.1NP_001157717.1  protein odr-4 homolog isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AL596220, AY854248, BC003397, DB116803, DQ529299
    Consensus CDS
    CCDS53449.1
    UniProtKB/Swiss-Prot
    Q5SWX8
    Related
    ENSP00000356440.3, ENST00000367470.8
    Conserved Domains (1) summary
    pfam14778
    Location:28362
    ODR4-like; Olfactory receptor 4-like
  2. NM_001164246.1NP_001157718.1  protein odr-4 homolog isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (3) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AK298107, AL596220, AY854248, BC003397, DB116803
    Consensus CDS
    CCDS53450.1
    UniProtKB/Swiss-Prot
    Q5SWX8
    Related
    ENSP00000395084.3, ENST00000419367.8
    Conserved Domains (1) summary
    pfam14778
    Location:28353
    ODR4-like; Olfactory receptor 4-like
  3. NM_017847.6NP_060317.3  protein odr-4 homolog isoform 1

    See identical proteins and their annotated locations for NP_060317.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AL596220, AY854248, BC003397, DB116803
    Consensus CDS
    CCDS53448.1
    UniProtKB/Swiss-Prot
    Q5SWX8
    Related
    ENSP00000287859.6, ENST00000287859.11
    Conserved Domains (1) summary
    pfam14778
    Location:28385
    ODR4-like; Olfactory receptor 4-like

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    186375758..186421375
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011509661.2XP_011507963.1  protein odr-4 homolog isoform X2

    Conserved Domains (1) summary
    pfam14778
    Location:28385
    ODR4-like; Olfactory receptor 4-like
  2. XM_011509660.2XP_011507962.1  protein odr-4 homolog isoform X1

    See identical proteins and their annotated locations for XP_011507962.1

    UniProtKB/Swiss-Prot
    Q5SWX8
    Conserved Domains (1) summary
    pfam14778
    Location:28385
    ODR4-like; Olfactory receptor 4-like
  3. XM_017001543.2XP_016857032.1  protein odr-4 homolog isoform X3

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