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ODR4 odr-4 GPCR localization factor homolog [ Homo sapiens (human) ]

Gene ID: 54953, updated on 27-Nov-2024

Summary

Official Symbol
ODR4provided by HGNC
Official Full Name
odr-4 GPCR localization factor homologprovided by HGNC
Primary source
HGNC:HGNC:24299
See related
Ensembl:ENSG00000157181 MIM:609335; AllianceGenome:HGNC:24299
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TTG1; odr-4; C1orf27
Summary
Predicted to be involved in protein localization. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in thyroid (RPKM 12.6), prostate (RPKM 9.5) and 25 other tissues See more
Orthologs
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Genomic context

See ODR4 in Genome Data Viewer
Location:
1q31.1
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (186375838..186435031)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (185730569..185776136)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (186344970..186390507)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904471 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:186214031-186214197 Neighboring gene RNA, U6 small nuclear 1240, pseudogene Neighboring gene proteoglycan 4 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:186312648-186313847 Neighboring gene MPRA-validated peak515 silencer Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:186323778-186324977 Neighboring gene translocated promoter region, nuclear basket protein Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1648 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2246 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2247 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2248 Neighboring gene PDC antisense RNA 1 Neighboring gene phosducin Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:186481023-186481524 Neighboring gene parkin coregulated like pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ20505

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein odr-4 homolog
Names
LAG1-interacting protein
odorant response abnormal 4
transactivated by recombinant transforming growth factor beta 1
transactivated by transforming growth factor beta protein 1
NP_001157717.1
NP_001157718.1
NP_060317.3
XP_011507962.1
XP_016857032.1
XP_047279394.1
XP_047279395.1
XP_047279396.1
XP_054193232.1
XP_054193233.1
XP_054193234.1
XP_054193235.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164245.2NP_001157717.1  protein odr-4 homolog isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AL596220, AY854248, BC003397, DB116803, DQ529299
    Consensus CDS
    CCDS53449.1
    UniProtKB/Swiss-Prot
    Q5SWX8
    Related
    ENSP00000356440.3, ENST00000367470.8
    Conserved Domains (1) summary
    pfam14778
    Location:28362
    ODR4-like; Olfactory receptor 4-like
  2. NM_001164246.2NP_001157718.1  protein odr-4 homolog isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (3) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AK298107, AL596220, AY854248, BC003397, DB116803
    Consensus CDS
    CCDS53450.1
    UniProtKB/Swiss-Prot
    Q5SWX8
    Related
    ENSP00000395084.3, ENST00000419367.8
    Conserved Domains (1) summary
    pfam14778
    Location:28353
    ODR4-like; Olfactory receptor 4-like
  3. NM_017847.6NP_060317.3  protein odr-4 homolog isoform 1

    See identical proteins and their annotated locations for NP_060317.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AL596220, AY854248, BC003397, DB116803
    Consensus CDS
    CCDS53448.1
    UniProtKB/Swiss-Prot
    B4DNY0, E9PFR7, Q19CC6, Q5SWX8, Q8WYB6, Q9BTS2, Q9H6A6, Q9NX06
    Related
    ENSP00000287859.6, ENST00000287859.11
    Conserved Domains (1) summary
    pfam14778
    Location:28385
    ODR4-like; Olfactory receptor 4-like

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    186375838..186435031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047423438.1XP_047279394.1  protein odr-4 homolog isoform X1

    UniProtKB/Swiss-Prot
    B4DNY0, E9PFR7, Q19CC6, Q5SWX8, Q8WYB6, Q9BTS2, Q9H6A6, Q9NX06
  2. XM_011509660.3XP_011507962.1  protein odr-4 homolog isoform X1

    See identical proteins and their annotated locations for XP_011507962.1

    UniProtKB/Swiss-Prot
    B4DNY0, E9PFR7, Q19CC6, Q5SWX8, Q8WYB6, Q9BTS2, Q9H6A6, Q9NX06
    Conserved Domains (1) summary
    pfam14778
    Location:28385
    ODR4-like; Olfactory receptor 4-like
  3. XM_047423439.1XP_047279395.1  protein odr-4 homolog isoform X2

  4. XM_047423440.1XP_047279396.1  protein odr-4 homolog isoform X3

  5. XM_017001543.3XP_016857032.1  protein odr-4 homolog isoform X4

RNA

  1. XR_007061319.1 RNA Sequence

  2. XR_007061320.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    185730569..185776136
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054337257.1XP_054193232.1  protein odr-4 homolog isoform X1

  2. XM_054337258.1XP_054193233.1  protein odr-4 homolog isoform X2

  3. XM_054337259.1XP_054193234.1  protein odr-4 homolog isoform X3

  4. XM_054337260.1XP_054193235.1  protein odr-4 homolog isoform X4

RNA

  1. XR_008486081.1 RNA Sequence