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OCIAD1 OCIA domain containing 1 [ Homo sapiens (human) ]

Gene ID: 54940, updated on 22-May-2020

Summary

Official Symbol
OCIAD1provided by HGNC
Official Full Name
OCIA domain containing 1provided by HGNC
Primary source
HGNC:HGNC:16074
See related
Ensembl:ENSG00000109180
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OCIA; ASRIJ; TPA018
Expression
Ubiquitous expression in thyroid (RPKM 53.3), brain (RPKM 50.0) and 25 other tissues See more
Orthologs

Genomic context

See OCIAD1 in Genome Data Viewer
Location:
4p11
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (48830924..48861817)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (48832599..48863834)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene zygote arrest 1 Neighboring gene FRY like transcription coactivator Neighboring gene RNA, U5E small nuclear 3, pseudogene Neighboring gene OCIAD1 antisense RNA 1 Neighboring gene OCIA domain containing 2 Neighboring gene RNA, U6 small nuclear 158, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of OCIA domain containing 1 (OCIAD1) by shRNA library screening inhibits HIV-1 replication in cultured Jurkat T-cells PubMed

Protein interactions

Protein Gene Interaction Pubs
Nef nef The yeast two-hybrid screen identifies the HIV-1 Nef interacting human protein OCIA domain containing 1 (OCIAD1) in cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20455, MGC111072

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of stem cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endosome ISS
Inferred from Sequence or Structural Similarity
more info
 
membrane HDA PubMed 

General protein information

Preferred Names
OCIA domain-containing protein 1
Names
ovarian cancer immunoreactive antigen domain containing 1
ovarian cancer immunoreactive antigen domain containing 1A
ovarian carcinoma immunoreactive antigen

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079839.2NP_001073308.1  OCIA domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001073308.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different splice site in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AI038315, BC088361, BI549536, BM999322
    Consensus CDS
    CCDS3484.1
    UniProtKB/Swiss-Prot
    Q9NX40
    UniProtKB/TrEMBL
    A0A024R9U3
    Related
    ENSP00000370882.3, ENST00000381473.7
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  2. NM_001079840.2NP_001073309.1  OCIA domain-containing protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001073309.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. Both variants 3 and 5 encode the same isoform.
    Source sequence(s)
    AI038315, AL539411, BM999322, BQ272551, DA037995
    Consensus CDS
    CCDS47052.1
    UniProtKB/Swiss-Prot
    Q9NX40
    Related
    ENSP00000399656.2, ENST00000444354.6
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  3. NM_001079841.2NP_001073310.1  OCIA domain-containing protein 1 isoform 3

    See identical proteins and their annotated locations for NP_001073310.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AF324350, AI038315, BM999322, BQ272551, DA037995
    Consensus CDS
    CCDS43228.1
    UniProtKB/Swiss-Prot
    Q9NX40
    Related
    ENSP00000379725.2, ENST00000396448.6
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  4. NM_001079842.2NP_001073311.2  OCIA domain-containing protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001073311.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) uses a different splice site in the 5' UTR, and lacks an in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (2) is shorter than isoform 1. Both variants 3 and 5 encode the same isoform.
    Source sequence(s)
    AI038315, BI549536, BM999322, BQ272551, CD515566
    Consensus CDS
    CCDS47052.1
    UniProtKB/Swiss-Prot
    Q9NX40
    Related
    ENSP00000416943.2, ENST00000425583.6
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  5. NM_001168254.1NP_001161726.1  OCIA domain-containing protein 1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (4) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AC079927, AI038315, AL519557, BM999322
    Conserved Domains (1) summary
    pfam07051
    Location:20116
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  6. NM_017830.4NP_060300.1  OCIA domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_060300.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1. Both variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AF251296, AI038315, BM999322, DA037995
    Consensus CDS
    CCDS3484.1
    UniProtKB/Swiss-Prot
    Q9NX40
    UniProtKB/TrEMBL
    A0A024R9U3
    Related
    ENSP00000264312.7, ENST00000264312.11
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    48830924..48861817
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024454108.1XP_024309876.1  OCIA domain-containing protein 1 isoform X2

    Related
    ENSP00000424041.1, ENST00000509122.5
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  2. XM_024454112.1XP_024309880.1  OCIA domain-containing protein 1 isoform X5

    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  3. XM_024454109.1XP_024309877.1  OCIA domain-containing protein 1 isoform X3

    Conserved Domains (1) summary
    pfam07051
    Location:39124
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  4. XM_024454113.1XP_024309881.1  OCIA domain-containing protein 1 isoform X6

    Related
    ENSP00000427389.1, ENST00000511102.5
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  5. XM_024454111.1XP_024309879.1  OCIA domain-containing protein 1 isoform X5

    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  6. XM_024454110.1XP_024309878.1  OCIA domain-containing protein 1 isoform X4

    Conserved Domains (1) summary
    pfam07051
    Location:39124
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  7. XM_024454105.1XP_024309873.1  OCIA domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    pfam07051
    Location:39124
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  8. XM_024454106.1XP_024309874.1  OCIA domain-containing protein 1 isoform X2

    Related
    ENSP00000423909.2, ENST00000513391.2
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  9. XM_017008329.1XP_016863818.1  OCIA domain-containing protein 1 isoform X6

    UniProtKB/Swiss-Prot
    Q9NX40
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  10. XM_024454114.1XP_024309882.1  OCIA domain-containing protein 1 isoform X6

    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)
  11. XM_024454107.1XP_024309875.1  OCIA domain-containing protein 1 isoform X2

    Related
    ENSP00000423002.1, ENST00000508293.5
    Conserved Domains (1) summary
    pfam07051
    Location:24109
    OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)

RNA

  1. XR_002959740.1 RNA Sequence

  2. XR_001741265.1 RNA Sequence

  3. XR_002959739.1 RNA Sequence

  4. XR_001741266.1 RNA Sequence

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