nudt5 nudix hydrolase 5 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: nudt5provided by Xenbase
Official Full Name: nudix hydrolase 5provided by Xenbase
Primary source: Xenbase:XB-GENE-980634
See related: Ensembl:ENSXETG00000021953 AllianceGenome:Xenbase:XB-GENE-980634
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable ADP-ribose diphosphatase activity. Predicted to be involved in nucleoside phosphate metabolic process and ribose phosphate metabolic process. Predicted to be active in nucleus. Orthologous to human NUDT5 (nudix hydrolase 5). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	3	NC_030679.2 (82261653..82273016)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	3	NC_030679.1 (72666985..72678312)

Chromosome 3 - NC_030679.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ADP-ribose diphosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables pyrophosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in nucleoside phosphate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribose phosphate metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ADP-sugar pyrophosphatase

Names: nudix (nucleoside diphosphate linked moiety X)-type motif 5

NP_001016613.1

EC 3.6.1.13

XP_012814487.1

EC 3.6.1.13

XP_017947577.1

EC 3.6.1.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001016613.2 → NP_001016613.1 ADP-sugar pyrophosphatase

See identical proteins and their annotated locations for NP_001016613.1

Status: PROVISIONAL

Source sequence(s)

CR760517

UniProtKB/TrEMBL

F6QJ70, Q28I97

Related

ENSXETP00000047503.3, ENSXETT00000047503.4

Conserved Domains (1) summary

cd03424
Location:62 → 209

ADPRase_NUDT5; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

82261653..82273016

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_012959033.3 → XP_012814487.1 ADP-sugar pyrophosphatase isoform X1

See identical proteins and their annotated locations for XP_012814487.1

UniProtKB/TrEMBL

F6QJ70, Q28I97

Conserved Domains (1) summary

cd03424
Location:62 → 209

ADPRase_NUDT5; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, ...
XM_018092088.2 → XP_017947577.1 ADP-sugar pyrophosphatase isoform X1

UniProtKB/TrEMBL

F6QJ70, Q28I97

Related

ENSXETP00000070336.1, ENSXETT00000086098.2

Conserved Domains (1) summary

cd03424
Location:62 → 209

ADPRase_NUDT5; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, ...