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TMEM161A transmembrane protein 161A [ Homo sapiens (human) ]

Gene ID: 54929, updated on 22-Sep-2022

Summary

Official Symbol
TMEM161Aprovided by HGNC
Official Full Name
transmembrane protein 161Aprovided by HGNC
Primary source
HGNC:HGNC:26020
See related
Ensembl:ENSG00000064545 MIM:618966; AllianceGenome:HGNC:26020
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AROS29; AROS-29
Summary
Involved in several processes, including cellular response to UV; regulation of response to DNA damage stimulus; and response to retinoic acid. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in prostate (RPKM 6.2), endometrium (RPKM 5.9) and 25 other tissues See more
Orthologs
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Genomic context

See TMEM161A in Genome Data Viewer
Location:
19p13.11
Exon count:
12
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (19119169..19138478, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (19255708..19275014, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (19229978..19249287, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904655 Neighboring gene solute carrier family 25 member 42 Neighboring gene Sharpr-MPRA regulatory region 5014 Neighboring gene BORCS8-MEF2B readthrough Neighboring gene myocyte enhancer factor 2B Neighboring gene BLOC-1 related complex subunit 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20422, FLJ39645

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 161A
Names
adaptive response to oxidative stress protein 29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256766.3NP_001243695.1  transmembrane protein 161A isoform 2 precursor

    See identical proteins and their annotated locations for NP_001243695.1

    Status: VALIDATED

    Source sequence(s)
    AC002126
    Consensus CDS
    CCDS58656.1
    UniProtKB/Swiss-Prot
    Q9NX61
    Related
    ENSP00000404208.2, ENST00000450333.6
    Conserved Domains (1) summary
    pfam10268
    Location:2373
    Tmemb_161AB; Predicted transmembrane protein 161AB
  2. NM_001411131.1NP_001398060.1  transmembrane protein 161A isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC002126
  3. NM_017814.3NP_060284.1  transmembrane protein 161A isoform 1 precursor

    See identical proteins and their annotated locations for NP_060284.1

    Status: VALIDATED

    Source sequence(s)
    AC002126, AK096964, BC005210, DA268563, DB311771, DB353676
    Consensus CDS
    CCDS12393.1
    UniProtKB/Swiss-Prot
    Q7L2Y1, Q9NX61
    Related
    ENSP00000162044.7, ENST00000162044.14
    Conserved Domains (1) summary
    pfam10268
    Location:2476
    Tmemb_161AB; Predicted transmembrane protein 161AB

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    19119169..19138478 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026916.2XP_016882405.1  transmembrane protein 161A isoform X2

    UniProtKB/TrEMBL
    K7EPA3
    Related
    ENSP00000467300.2, ENST00000587583.6
  2. XM_047439023.1XP_047294979.1  transmembrane protein 161A isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    19255708..19275014 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)