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TMEM260 transmembrane protein 260 [ Homo sapiens (human) ]

Gene ID: 54916, updated on 22-Sep-2022

Summary

Official Symbol
TMEM260provided by HGNC
Official Full Name
transmembrane protein 260provided by HGNC
Primary source
HGNC:HGNC:20185
See related
Ensembl:ENSG00000070269 MIM:617449; AllianceGenome:HGNC:20185
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SHDRA; C14orf101
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thyroid (RPKM 3.9), ovary (RPKM 3.6) and 25 other tissues See more
Orthologs
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Genomic context

See TMEM260 in Genome Data Viewer
Location:
14q22.3
Exon count:
24
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (56579525..56663165)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (50785541..50855286)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (57046516..57116233)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903321 Neighboring gene uncharacterized LOC101927690 Neighboring gene U2 spliceosomal RNA Neighboring gene ribosomal protein L36a pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20392

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 260
Names
UPF0679 protein C14orf101

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017799.4NP_060269.3  transmembrane protein 260

    See identical proteins and their annotated locations for NP_060269.3

    Status: VALIDATED

    Source sequence(s)
    AK023885, AK056291, AL161757, BX647387
    Consensus CDS
    CCDS9727.2
    UniProtKB/Swiss-Prot
    Q86XE1, Q9NX78
    UniProtKB/TrEMBL
    B3KN73
    Related
    ENSP00000261556.6, ENST00000261556.11
    Conserved Domains (1) summary
    pfam11028
    Location:52206
    DUF2723; Protein of unknown function (DUF2723)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    56579525..56663165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047431494.1XP_047287450.1  transmembrane protein 260 isoform X3

  2. XM_011536851.3XP_011535153.1  transmembrane protein 260 isoform X1

    Conserved Domains (1) summary
    pfam11028
    Location:52206
    DUF2723; Protein of unknown function (DUF2723)
  3. XM_047431497.1XP_047287453.1  transmembrane protein 260 isoform X6

    Related
    ENSP00000441934.1, ENST00000538838.5
  4. XM_047431495.1XP_047287451.1  transmembrane protein 260 isoform X4

  5. XM_047431496.1XP_047287452.1  transmembrane protein 260 isoform X5

  6. XM_047431493.1XP_047287449.1  transmembrane protein 260 isoform X3

  7. XM_011536852.2XP_011535154.1  transmembrane protein 260 isoform X2

  8. XM_047431498.1XP_047287454.1  transmembrane protein 260 isoform X7

RNA

  1. XR_007064017.1 RNA Sequence

  2. XR_007064018.1 RNA Sequence

  3. XR_007064019.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    50785541..50855286
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)