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RPP25 ribonuclease P and MRP subunit p25 [ Homo sapiens (human) ]

Gene ID: 54913, updated on 5-Jan-2020

Summary

Official Symbol
RPP25provided by HGNC
Official Full Name
ribonuclease P and MRP subunit p25provided by HGNC
Primary source
HGNC:HGNC:30361
See related
Ensembl:ENSG00000178718
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs

Genomic context

See RPP25 in Genome Data Viewer
Location:
15q24.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (74954418..74956772, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (75247443..75249775, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene mannose phosphate isomerase Neighboring gene family with sequence similarity 219 member B Neighboring gene cytochrome c oxidase subunit 5A Neighboring gene uncharacterized LOC107984731 Neighboring gene secretory carrier membrane protein 5

Genomic regions, transcripts, and products

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20374

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ribonuclease P RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to ribonuclease P activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
RNA phosphodiester bond hydrolysis, endonucleolytic IEA
Inferred from Electronic Annotation
more info
 
rRNA processing IEA
Inferred from Electronic Annotation
more info
 
tRNA 5'-leader removal IDA
Inferred from Direct Assay
more info
PubMed 
tRNA 5'-leader removal TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
centriolar satellite IDA
Inferred from Direct Assay
more info
 
multimeric ribonuclease P complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 
ribonuclease MRP complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ribonuclease P protein subunit p25
Names
RNase P protein subunit p25
ribonuclease P 25kDa subunit
ribonuclease P/MRP 25kDa subunit
ribonuclease P/MRP subunit p25
NP_060263.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017793.3NP_060263.2  ribonuclease P protein subunit p25

    See identical proteins and their annotated locations for NP_060263.2

    Status: VALIDATED

    Source sequence(s)
    AC015720
    Consensus CDS
    CCDS10274.1
    UniProtKB/Swiss-Prot
    Q9BUL9
    Related
    ENSP00000317691.5, ENST00000322177.5
    Conserved Domains (1) summary
    pfam01918
    Location:37101
    Alba; Alba

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    74954418..74956772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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