Format

Send to:

Choose Destination

RPP25 ribonuclease P and MRP subunit p25 [ Homo sapiens (human) ]

Gene ID: 54913, updated on 7-Aug-2021

Summary

Official Symbol
RPP25provided by HGNC
Official Full Name
ribonuclease P and MRP subunit p25provided by HGNC
Primary source
HGNC:HGNC:30361
See related
Ensembl:ENSG00000178718 MIM:619235
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See RPP25 in Genome Data Viewer
Location:
15q24.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (74954418..74956772, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (75246759..75249113, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene mannose phosphate isomerase Neighboring gene family with sequence similarity 219 member B Neighboring gene cytochrome c oxidase subunit 5A Neighboring gene uncharacterized LOC107984731 Neighboring gene secretory carrier membrane protein 5

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20374

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ribonuclease P RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to ribonuclease P activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in RNA phosphodiester bond hydrolysis, endonucleolytic IEA
Inferred from Electronic Annotation
more info
 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA 5'-leader removal IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tRNA 5'-leader removal IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in centriolar satellite IDA
Inferred from Direct Assay
more info
 
part_of multimeric ribonuclease P complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
part_of ribonuclease MRP complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of ribonuclease MRP complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ribonuclease P protein subunit p25
Names
RNase P protein subunit p25
ribonuclease P 25kDa subunit
ribonuclease P/MRP 25kDa subunit
ribonuclease P/MRP subunit p25
NP_060263.2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017793.3NP_060263.2  ribonuclease P protein subunit p25

    See identical proteins and their annotated locations for NP_060263.2

    Status: VALIDATED

    Source sequence(s)
    AC015720
    Consensus CDS
    CCDS10274.1
    UniProtKB/Swiss-Prot
    Q9BUL9
    Related
    ENSP00000317691.6, ENST00000322177.6
    Conserved Domains (1) summary
    pfam01918
    Location:37101
    Alba

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    74954418..74956772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center