XB5763442 provisional ortholog of chitinase acidic [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Symbol: XB5763442provided by Xenbase
Full Name: provisional ortholog of chitinase acidicprovided by Xenbase
Primary source: Xenbase:XB-GENE-5763443
See related: Ensembl:ENSXETG00000011839 AllianceGenome:Xenbase:XB-GENE-5763443
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable chitin binding activity and chitinase activity. Predicted to act upstream of or within carbohydrate metabolic process and chitin catabolic process. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 2

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	2	NC_030678.2 (70596510..70624495)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	2	NC_030678.1 (62226631..62250735)

Chromosome 2 - NC_030678.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables chitin binding	IEA Inferred from Electronic Annotation more info
enables chitinase activity	IEA Inferred from Electronic Annotation more info
enables endochitinase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, hydrolyzing O-glycosyl compounds	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chitin catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within polysaccharide catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in extracellular region	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein LOC548945

Names: chitinase-like, acidic

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001016191.2 → NP_001016191.1 uncharacterized protein LOC548945 precursor

See identical proteins and their annotated locations for NP_001016191.1

Status: VALIDATED

Source sequence(s)

CR761799

UniProtKB/TrEMBL

B1H1D5, F6RI49

Related

ENSXETP00000091612.1, ENSXETT00000104365.2

Conserved Domains (3) summary

cd02872
Location:18 → 383

GH18_chitolectin_chitotriosidase; This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active ...

smart00636
Location:17 → 361

Glyco_18; Glyco_18 domain

pfam01607
Location:434 → 480

CBM_14; Chitin binding Peritrophin-A domain