Format

Send to:

Choose Destination

GPATCH4 G-patch domain containing 4 [ Homo sapiens (human) ]

Gene ID: 54865, updated on 3-May-2020

Summary

Official Symbol
GPATCH4provided by HGNC
Official Full Name
G-patch domain containing 4provided by HGNC
Primary source
HGNC:HGNC:25982
See related
Ensembl:ENSG00000160818
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GPATC4
Expression
Ubiquitous expression in appendix (RPKM 11.6), brain (RPKM 10.3) and 25 other tissues See more
Orthologs

Genomic context

See GPATCH4 in Genome Data Viewer
Location:
1q22-q23.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (156594301..156601487, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (156564100..156571288, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene IQ motif containing GTPase activating protein 3 Neighboring gene tetratricopeptide repeat domain 24 Neighboring gene NAD(P)HX epimerase Neighboring gene hyaluronan and proteoglycan link protein 2 Neighboring gene uncharacterized LOC101928177 Neighboring gene uncharacterized LOC105371453 Neighboring gene brevican

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Rev rev HIV-1 Rev is identified to have a physical interaction with G patch domain containing 4 (GPATCH4) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
G patch domain-containing protein 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015590.3NP_056405.2  G patch domain-containing protein 4 isoform 1

    See identical proteins and their annotated locations for NP_056405.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) lacks an internal segment in the 5' region, resulting in an upstream AUG start codon, as compared to variant 2. The resulting isoform (1) has a longer and distinct N-terminus, as compared to isoform 2.
    Source sequence(s)
    AK293026, BC056904, BE326312, CB109133, DA087471
    Consensus CDS
    CCDS44245.1
    UniProtKB/TrEMBL
    A8KAG1, E9PAV9
    Related
    ENSP00000396441.2, ENST00000438976.6
    Conserved Domains (1) summary
    pfam01585
    Location:1360
    G-patch; G-patch domain
  2. NM_182679.3NP_872620.1  G patch domain-containing protein 4 isoform 2

    See identical proteins and their annotated locations for NP_872620.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) is the longer and predominant transcript, which encodes a shorter isoform (2).
    Source sequence(s)
    AK293026, AL365181, BC056904, BE326312, DA087471
    Consensus CDS
    CCDS1146.1
    UniProtKB/TrEMBL
    A0A0A0MRK1, A8KAG1
    Related
    ENSP00000357215.4, ENST00000368232.8
    Conserved Domains (1) summary
    pfam01585
    Location:855
    G-patch; G-patch domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    156594301..156601487 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005245287.4XP_005245344.1  G patch domain-containing protein 4 isoform X1

    Conserved Domains (1) summary
    pfam01585
    Location:855
    G-patch; G-patch domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_017725.1: Suppressed sequence

    Description
    NM_017725.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Support Center