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PAQR5 progestin and adipoQ receptor family member 5 [ Homo sapiens (human) ]

Gene ID: 54852, updated on 21-Dec-2019

Summary

Official Symbol
PAQR5provided by HGNC
Official Full Name
progestin and adipoQ receptor family member 5provided by HGNC
Primary source
HGNC:HGNC:29645
See related
Ensembl:ENSG00000137819 MIM:607781
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MPRG
Expression
Biased expression in kidney (RPKM 13.9), adrenal (RPKM 5.4) and 9 other tissues See more
Orthologs

Genomic context

See PAQR5 in Genome Data Viewer
Location:
15q23
Exon count:
18
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (69284134..69407780)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (69591294..69699976)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 47 member C pseudogene Neighboring gene glucuronic acid epimerase Neighboring gene RNA, 7SL, cytoplasmic 438, pseudogene Neighboring gene uncharacterized LOC102723548 Neighboring gene Sharpr-MPRA regulatory region 4882 Neighboring gene uncharacterized LOC145694 Neighboring gene fumarylacetoacetate hydrolase domain containing 1 pseudogene Neighboring gene kinesin family member 23 Neighboring gene ribosomal protein lateral stalk subunit P1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20190

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
steroid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
oogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
membrane progestin receptor gamma
Names
mPR gamma
membrane progesterone P4 receptor gamma
membrane progesterone receptor gamma
progesterone and adipoQ receptor family member 5
progestin and adipoQ receptor family member V

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104554.1NP_001098024.1  membrane progestin receptor gamma

    See identical proteins and their annotated locations for NP_001098024.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC027237, AW779994, AY424283, BC039234
    Consensus CDS
    CCDS10232.1
    UniProtKB/Swiss-Prot
    Q9NXK6
    UniProtKB/TrEMBL
    A0A024R607
    Conserved Domains (1) summary
    pfam03006
    Location:43269
    HlyIII; Haemolysin-III related
  2. NM_017705.4NP_060175.3  membrane progestin receptor gamma

    See identical proteins and their annotated locations for NP_060175.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC026992, AC027237, AW779994, BC039234, BE747523
    Consensus CDS
    CCDS10232.1
    UniProtKB/Swiss-Prot
    Q9NXK6
    UniProtKB/TrEMBL
    A0A024R607
    Related
    ENSP00000378803.2, ENST00000395407.7
    Conserved Domains (1) summary
    pfam03006
    Location:43269
    HlyIII; Haemolysin-III related

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    69284134..69407780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017022364.1XP_016877853.1  membrane progestin receptor gamma isoform X1

    UniProtKB/Swiss-Prot
    Q9NXK6
    UniProtKB/TrEMBL
    A0A024R607
    Conserved Domains (1) summary
    pfam03006
    Location:43269
    HlyIII; Haemolysin-III related
  2. XM_017022368.1XP_016877857.1  membrane progestin receptor gamma isoform X8

  3. XM_017022360.1XP_016877849.1  membrane progestin receptor gamma isoform X1

    UniProtKB/Swiss-Prot
    Q9NXK6
    UniProtKB/TrEMBL
    A0A024R607
    Conserved Domains (1) summary
    pfam03006
    Location:43269
    HlyIII; Haemolysin-III related
  4. XM_017022362.1XP_016877851.1  membrane progestin receptor gamma isoform X1

    UniProtKB/Swiss-Prot
    Q9NXK6
    UniProtKB/TrEMBL
    A0A024R607
    Conserved Domains (1) summary
    pfam03006
    Location:43269
    HlyIII; Haemolysin-III related
  5. XM_011521720.2XP_011520022.1  membrane progestin receptor gamma isoform X1

    See identical proteins and their annotated locations for XP_011520022.1

    UniProtKB/Swiss-Prot
    Q9NXK6
    UniProtKB/TrEMBL
    A0A024R607
    Conserved Domains (1) summary
    pfam03006
    Location:43269
    HlyIII; Haemolysin-III related
  6. XM_017022366.1XP_016877855.1  membrane progestin receptor gamma isoform X6

    Conserved Domains (1) summary
    cl03831
    Location:14154
    HlyIII; Haemolysin-III related
  7. XM_011521727.2XP_011520029.1  membrane progestin receptor gamma isoform X7

    Conserved Domains (1) summary
    cl03831
    Location:43204
    HlyIII; Haemolysin-III related
  8. XM_011521723.2XP_011520025.1  membrane progestin receptor gamma isoform X3

    Conserved Domains (1) summary
    pfam03006
    Location:1225
    HlyIII; Haemolysin-III related
  9. XM_011521725.2XP_011520027.1  membrane progestin receptor gamma isoform X5

    Conserved Domains (1) summary
    cl03831
    Location:68158
    HlyIII; Haemolysin-III related
  10. XM_024449966.1XP_024305734.1  membrane progestin receptor gamma isoform X1

    Related
    ENSP00000453526.1, ENST00000561153.5
    Conserved Domains (1) summary
    pfam03006
    Location:43269
    HlyIII; Haemolysin-III related
  11. XM_017022361.1XP_016877850.1  membrane progestin receptor gamma isoform X1

    UniProtKB/Swiss-Prot
    Q9NXK6
    UniProtKB/TrEMBL
    A0A024R607
    Conserved Domains (1) summary
    pfam03006
    Location:43269
    HlyIII; Haemolysin-III related
  12. XM_017022363.1XP_016877852.1  membrane progestin receptor gamma isoform X1

    UniProtKB/Swiss-Prot
    Q9NXK6
    UniProtKB/TrEMBL
    A0A024R607
    Conserved Domains (1) summary
    pfam03006
    Location:43269
    HlyIII; Haemolysin-III related
  13. XM_005254495.4XP_005254552.1  membrane progestin receptor gamma isoform X2

    See identical proteins and their annotated locations for XP_005254552.1

    Conserved Domains (1) summary
    pfam03006
    Location:29255
    HlyIII; Haemolysin-III related
  14. XM_024449967.1XP_024305735.1  membrane progestin receptor gamma isoform X4

    Conserved Domains (1) summary
    cl03831
    Location:112202
    HlyIII; Haemolysin-III related
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