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ANKRD49 ankyrin repeat domain 49 [ Homo sapiens (human) ]

Gene ID: 54851, updated on 3-Oct-2020

Summary

Official Symbol
ANKRD49provided by HGNC
Official Full Name
ankyrin repeat domain 49provided by HGNC
Primary source
HGNC:HGNC:25970
See related
Ensembl:ENSG00000168876
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FGIF; GBIF
Expression
Ubiquitous expression in lymph node (RPKM 11.3), bone marrow (RPKM 10.6) and 25 other tissues See more
Orthologs

Genomic context

See ANKRD49 in Genome Data Viewer
Location:
11q21
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (94493984..94499578)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (94227153..94232744)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 83 Neighboring gene MRE11 homolog, double strand break repair nuclease Neighboring gene microRNA 548l Neighboring gene chromosome 11 open reading frame 97 Neighboring gene uncharacterized LOC105369438 Neighboring gene fucosyltransferase 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20189, FLJ20441

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IC
Inferred by Curator
more info
PubMed 

General protein information

Preferred Names
ankyrin repeat domain-containing protein 49
Names
fetal globin-inducing factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017704.3NP_060174.2  ankyrin repeat domain-containing protein 49

    See identical proteins and their annotated locations for NP_060174.2

    Status: VALIDATED

    Source sequence(s)
    AK057696, AL833977, AP000786, BC017798, BG025192
    Consensus CDS
    CCDS8300.1
    UniProtKB/Swiss-Prot
    Q8WVL7
    UniProtKB/TrEMBL
    A0A024R398
    Related
    ENSP00000440396.1, ENST00000544612.6
    Conserved Domains (3) summary
    sd00045
    Location:78105
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:112197
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:75128
    Ank_4; Ankyrin repeats (many copies)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    94493984..94499578
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017941.1XP_016873430.1  ankyrin repeat domain-containing protein 49 isoform X1

    UniProtKB/Swiss-Prot
    Q8WVL7
    UniProtKB/TrEMBL
    A0A024R398
    Conserved Domains (3) summary
    sd00045
    Location:78105
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:112197
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:75128
    Ank_4; Ankyrin repeats (many copies)
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