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chia chitinase, acidic [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 548404, updated on 14-Nov-2024

Summary

Official Symbol
chiaprovided by Xenbase
Official Full Name
chitinase, acidicprovided by Xenbase
Primary source
Xenbase:XB-GENE-5868468
See related
Ensembl:ENSXETG00000011843 AllianceGenome:Xenbase:XB-GENE-5868468
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
chia1
Summary
Predicted to enable chitin binding activity and chitinase activity. Predicted to act upstream of or within carbohydrate metabolic process and chitin catabolic process. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See chia in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (70631779..70643034, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (62260778..62280622, complement)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene BTG family member 2 Neighboring gene provisional ortholog of chitinase acidic Neighboring gene translocase of outer mitochondrial membrane 6 Neighboring gene ubiquitin specific peptidase 49

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables chitin binding IEA
Inferred from Electronic Annotation
more info
 
enables chitinase activity IEA
Inferred from Electronic Annotation
more info
 
enables endochitinase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within chitin catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within polysaccharide catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
acidic mammalian chitinase
NP_001186489.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199560.1NP_001186489.1  acidic mammalian chitinase precursor

    Status: VALIDATED

    Source sequence(s)
    BC090382, CF523087
    UniProtKB/TrEMBL
    F6RI40, Q5CZZ2
    Related
    ENSXETP00000025884.3, ENSXETT00000025884.5
    Conserved Domains (3) summary
    cd02872
    Location:24387
    GH18_chitolectin_chitotriosidase; This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active ...
    smart00636
    Location:26365
    Glyco_18; Glyco_18 domain
    pfam01607
    Location:436482
    CBM_14; Chitin binding Peritrophin-A domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    70631779..70643034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)