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KCTD9 potassium channel tetramerization domain containing 9 [ Homo sapiens (human) ]

Gene ID: 54793, updated on 13-Aug-2022

Summary

Official Symbol
KCTD9provided by HGNC
Official Full Name
potassium channel tetramerization domain containing 9provided by HGNC
Primary source
HGNC:HGNC:22401
See related
Ensembl:ENSG00000104756 MIM:617265; AllianceGenome:HGNC:22401
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BTBD27
Summary
Enables cullin family protein binding activity; identical protein binding activity; and protein self-association. Predicted to be involved in intracellular signal transduction; protein homooligomerization; and protein ubiquitination. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart (RPKM 8.3), esophagus (RPKM 7.8) and 25 other tissues See more
Orthologs
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Genomic context

See KCTD9 in Genome Data Viewer
Location:
8p21.2
Exon count:
13
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (25427847..25458433, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (25703069..25733653, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (25285363..25315949, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 10380 Neighboring gene uncharacterized LOC124901913 Neighboring gene gonadotropin releasing hormone 1 Neighboring gene cell division cycle associated 2 Neighboring gene Sharpr-MPRA regulatory region 1118 Neighboring gene uncharacterized LOC107986933 Neighboring gene uncharacterized LOC105379333

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20038

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cullin family protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein self-association IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in protein homooligomerization IEA
Inferred from Electronic Annotation
more info
 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
BTB/POZ domain-containing protein KCTD9
Names
potassium channel tetramerisation domain containing 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017634.4NP_060104.2  BTB/POZ domain-containing protein KCTD9

    See identical proteins and their annotated locations for NP_060104.2

    Status: VALIDATED

    Source sequence(s)
    AC103779, BC021216, BQ022851, DA115324
    Consensus CDS
    CCDS6048.1
    UniProtKB/Swiss-Prot
    Q7L273, Q9NXV4
    Related
    ENSP00000221200.4, ENST00000221200.9
    Conserved Domains (3) summary
    COG1357
    Location:168378
    YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
    cd17073
    Location:266
    KHA; dimerization domain of potassium ion channel, similar to doublecortin-like domain, found in potassium channel tetramerization domain containing 9 (KCTD9) and similar proteins
    cd18368
    Location:89188
    BTB_POZ_KCTD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 9 (KCTD9)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    25427847..25458433 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047421912.1XP_047277868.1  BTB/POZ domain-containing protein KCTD9 isoform X2

  2. XM_047421913.1XP_047277869.1  BTB/POZ domain-containing protein KCTD9 isoform X2

  3. XM_047421914.1XP_047277870.1  BTB/POZ domain-containing protein KCTD9 isoform X2

  4. XM_047421915.1XP_047277871.1  BTB/POZ domain-containing protein KCTD9 isoform X2

  5. XM_047421911.1XP_047277867.1  BTB/POZ domain-containing protein KCTD9 isoform X1

    Conserved Domains (3) summary
    COG1357
    Location:216308
    YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
    cd17073
    Location:266
    KHA; dimerization domain of potassium ion channel, similar to doublecortin-like domain, found in potassium channel tetramerization domain containing 9 (KCTD9) and similar proteins
    cd18368
    Location:89188
    BTB_POZ_KCTD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 9 (KCTD9)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    25703069..25733653 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)