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BBOV_II000780 dihydrofolate reductase/thymidilate synthase [ Babesia bovis T2Bo ]

Gene ID: 5477830, updated on 17-May-2024
Gene symbol
BBOV_II000780
Gene description
dihydrofolate reductase/thymidilate synthase
Locus tag
BBOV_II000780
See related
PiroplasmaDB:BBOV_II000780; VEuPathDB:BBOV_II000780
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Babesia bovis T2Bo (strain: T2Bo)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida; Babesiidae; Babesia
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See BBOV_II000780 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
4
Sequence:
Chromosome: 2; NC_010574.1 (201769..204032)

Chromosome 2 - NC_010574.1Genomic Context describing neighboring genes Neighboring gene protein kinase domain containing protein Neighboring gene putative integral membrane protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic Sequence:
NC_010574.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Begley DW, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2011 Sep 1. PMID 21904052, Free PMC Article
  2. Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa. Brayton KA, et al. PLoS Pathog, 2007 Oct 19. PMID 17953480, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dihydrofolate reductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables thymidylate synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dTMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in one-carbon metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
dihydrofolate reductase/thymidilate synthase

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_010574.1 Reference assembly

    Range
    201769..204032
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001609556.2 → XP_001609606.1  dihydrofolate reductase/thymidilate synthase [Babesia bovis T2Bo]

    See identical proteins and their annotated locations for XP_001609606.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A7ASX7, Q7Z0Z9
    Conserved Domains (1) summary
    PTZ00164
    Location:2 → 511
    PTZ00164; bifunctional dihydrofolate reductase-thymidylate synthase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
3I3R_A.1
3I3R_B.1
3KJR_A.1
3KJR_B.1

Gene LinkOut

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Molecular Biology Databases
Research Materials