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FNDC8 fibronectin type III domain containing 8 [ Homo sapiens (human) ]

Gene ID: 54752, updated on 1-Jun-2020

Summary

Official Symbol
FNDC8provided by HGNC
Official Full Name
fibronectin type III domain containing 8provided by HGNC
Primary source
HGNC:HGNC:25286
See related
Ensembl:ENSG00000073598
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 39.7) and brain (RPKM 1.6) See more
Orthologs

Genomic context

See FNDC8 in Genome Data Viewer
Location:
17q12
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (35121615..35130732)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (33448598..33457751)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene RAD51L3-RFFL readthrough Neighboring gene ring finger and FYVE like domain containing E3 ubiquitin protein ligase Neighboring gene ribosomal protein L37 pseudogene 22 Neighboring gene RAD51 paralog D Neighboring gene notchless homolog 1 Neighboring gene unc-45 myosin chaperone B Neighboring gene Spi-C transcription factor (Spi-1/PU.1 related) pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Clone Names

  • DKFZp434H2215

General protein information

Preferred Names
fibronectin type III domain-containing protein 8

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054719.1 RefSeqGene

    Range
    5037..14154
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_017559.4NP_060029.1  fibronectin type III domain-containing protein 8

    See identical proteins and their annotated locations for NP_060029.1

    Status: VALIDATED

    Source sequence(s)
    AK313775, AL133054, BC024002
    Consensus CDS
    CCDS11290.1
    UniProtKB/Swiss-Prot
    Q8TC99
    Related
    ENSP00000158009.4, ENST00000158009.6
    Conserved Domains (1) summary
    cd00063
    Location:179277
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    35121615..35130732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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