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Btnl2 butyrophilin-like 2 [ Mus musculus (house mouse) ]

Gene ID: 547431, updated on 12-Aug-2018

Summary

Official Symbol
Btnl2provided by MGI
Official Full Name
butyrophilin-like 2provided by MGI
Primary source
MGI:MGI:1859549
See related
Ensembl:ENSMUSG00000024340 Vega:OTTMUSG00000020172
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NG9; Btl2; BTLN2; Gm315; BTL-II
Expression
Biased expression in large intestine adult (RPKM 31.7), duodenum adult (RPKM 31.5) and 2 other tissues See more
Orthologs

Genomic context

See Btnl2 in Genome Data Viewer
Location:
17 B1; 17 17.98 cM
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (34354789..34369492)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (34491767..34506437)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene histocompatibility 2, class II antigen E beta2 Neighboring gene histocompatibility 2, class II antigen E alpha, pseudogene Neighboring gene butyrophilin-like 1 Neighboring gene predicted gene 15320 Neighboring gene non-histone chromosomal protein HMG-14-like

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signaling receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
T cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of T cell receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of interleukin-2 secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
butyrophilin-like protein 2
Names
butyrophylin-like MHC class II associated

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_079835.2NP_524574.1  butyrophilin-like protein 2

    See identical proteins and their annotated locations for NP_524574.1

    Status: PROVISIONAL

    Source sequence(s)
    AK136521
    Consensus CDS
    CCDS37585.1
    UniProtKB/Swiss-Prot
    O70355
    Related
    ENSMUSP00000025198.7, OTTMUSP00000021847, ENSMUST00000025198.13, OTTMUST00000047932
    Conserved Domains (3) summary
    cd05713
    Location:43142
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    smart00410
    Location:257358
    IG_like; Immunoglobulin like
    cl11960
    Location:379444
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

    Range
    34354789..34369492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006524645.3XP_006524708.1  butyrophilin-like protein 2 isoform X2

    See identical proteins and their annotated locations for XP_006524708.1

    Conserved Domains (3) summary
    cd05713
    Location:43142
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    smart00410
    Location:37141
    IG_like; Immunoglobulin like
    cl11960
    Location:260281
    Ig; Immunoglobulin domain
  2. XM_006524646.1XP_006524709.1  butyrophilin-like protein 2 isoform X3

    See identical proteins and their annotated locations for XP_006524709.1

    Conserved Domains (3) summary
    cd05713
    Location:43142
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    smart00410
    Location:37141
    IG_like; Immunoglobulin like
    cl11960
    Location:260279
    Ig; Immunoglobulin domain
  3. XM_017317579.1XP_017173068.1  butyrophilin-like protein 2 isoform X1

Reference GRCm38.p4 129X1/SvJ

Genomic

  1. NT_039662.3 Reference GRCm38.p4 129X1/SvJ

    Range
    603599..618269
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 NOD/MrkTac

Genomic

  1. NT_187027.1 Reference GRCm38.p4 NOD/MrkTac

    Range
    661518..676202
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 NOD/ShiLtJ

Genomic

  1. NT_187004.1 Reference GRCm38.p4 NOD/ShiLtJ

    Range
    661761..676444
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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