Format

Send to:

Choose Destination

LY6K lymphocyte antigen 6 family member K [ Homo sapiens (human) ]

Gene ID: 54742, updated on 1-Aug-2020

Summary

Official Symbol
LY6Kprovided by HGNC
Official Full Name
lymphocyte antigen 6 family member Kprovided by HGNC
Primary source
HGNC:HGNC:24225
See related
Ensembl:ENSG00000160886 MIM:615093
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT97; ly-6K; URLC10; HSJ001348
Expression
Biased expression in testis (RPKM 9.3), fat (RPKM 2.1) and 4 other tissues See more
Orthologs

Genomic context

See LY6K in Genome Data Viewer
Location:
8q24.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (142700081..142705127)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (143781529..143785588)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene Jrk helix-turn-helix protein Neighboring gene prostate stem cell antigen Neighboring gene lncRNA associated with ovarian cancer 1 Neighboring gene thioesterase superfamily member 6 Neighboring gene secreted LY6/PLAUR domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Clone Names

  • FLJ35226

Gene Ontology Provided by GOA

Process Evidence Code Pubs
binding of sperm to zona pellucida IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
acrosomal vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acrosomal vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
extracellular region TAS
Traceable Author Statement
more info
 
membrane raft IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
lymphocyte antigen 6K
Names
cancer/testis antigen 97
lymphocyte antigen 6 complex, locus K
up-regulated in lung cancer 10

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001160354.2NP_001153826.1  lymphocyte antigen 6K isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region that causes a frameshift, compared to variant 1. The resulting isoform (2) has a distinct and shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    BC001291, BG491223, CB528496
    UniProtKB/Swiss-Prot
    Q17RY6
  2. NM_001160355.2NP_001153827.1  lymphocyte antigen 6K isoform 3 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region that causes a frameshift, compared to variant 1. The resulting isoform (3) has a distinct and shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AI740834, BC001291, BG491223
    Consensus CDS
    CCDS59114.1
    UniProtKB/Swiss-Prot
    Q17RY6
    Related
    ENSP00000429695.1, ENST00000519387.1
  3. NM_017527.4NP_059997.3  lymphocyte antigen 6K isoform 1 precursor

    See identical proteins and their annotated locations for NP_059997.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC108002, BC001291, BG491223
    Consensus CDS
    CCDS6385.2
    UniProtKB/Swiss-Prot
    Q17RY6
    Related
    ENSP00000292430.6, ENST00000292430.10

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    142700081..142705127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005250990.5XP_005251047.1  lymphocyte antigen 6K isoform X2

  2. XM_005250989.5XP_005251046.1  lymphocyte antigen 6K isoform X1

Support Center