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Plxnc1 plexin C1 [ Mus musculus (house mouse) ]

Gene ID: 54712, updated on 9-Sep-2018

Summary

Official Symbol
Plxnc1provided by MGI
Official Full Name
plexin C1provided by MGI
Primary source
MGI:MGI:1890127
See related
Ensembl:ENSMUSG00000074785 Vega:OTTMUSG00000042667
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CD232; Vespr; AW742158; 2510048K12Rik
Expression
Broad expression in CNS E18 (RPKM 9.0), ovary adult (RPKM 7.4) and 17 other tissues See more
Orthologs

Genomic context

See Plxnc1 in Genome Data Viewer
Location:
10; 10 C2
Exon count:
32
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (94790866..94945275, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (94253611..94407212, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 32898 Neighboring gene centrosomal protein 83, opposite strand Neighboring gene centrosomal protein 83 Neighboring gene predicted gene, 40744 Neighboring gene predicted gene, 29684 Neighboring gene predicted gene, 33091

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
semaphorin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
negative regulation of cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cell shape IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
semaphorin-plexin signaling pathway IEA
Inferred from Electronic Annotation
more info
 
semaphorin-plexin signaling pathway involved in axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
semaphorin receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
plexin-C1
Names
viral-encoded semaphorin protein receptor
virus-encoded semaphorin protein receptor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018797.2NP_061267.1  plexin-C1 precursor

    See identical proteins and their annotated locations for NP_061267.1

    Status: VALIDATED

    Source sequence(s)
    AF190578, AK011113, BE948614
    Consensus CDS
    CCDS48676.1
    UniProtKB/Swiss-Prot
    Q9QZC2
    UniProtKB/TrEMBL
    Q9CRY9
    Related
    ENSMUSP00000096939.2, OTTMUSP00000063082, ENSMUST00000099337.4, OTTMUST00000112367
    Conserved Domains (5) summary
    cd11246
    Location:44453
    Sema_plexin_C1; The Sema domain, a protein interacting module, of Plexin C1
    smart00429
    Location:755847
    IPT; ig-like, plexins, transcription factors
    pfam01437
    Location:454507
    PSI; Plexin repeat
    pfam01833
    Location:666752
    TIG; IPT/TIG domain
    pfam08337
    Location:10181541
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

    Range
    94790866..94945275 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513895.3XP_006513958.1  plexin-C1 isoform X1

    Conserved Domains (5) summary
    cd11246
    Location:229638
    Sema_plexin_C1; The Sema domain, a protein interacting module, of Plexin C1
    smart00429
    Location:9401032
    IPT; ig-like, plexins, transcription factors
    pfam01437
    Location:639692
    PSI; Plexin repeat
    pfam01833
    Location:851937
    TIG; IPT/TIG domain
    pfam08337
    Location:12031725
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain
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