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GPN2 GPN-loop GTPase 2 [ Homo sapiens (human) ]

Gene ID: 54707, updated on 29-Mar-2020

Summary

Official Symbol
GPN2provided by HGNC
Official Full Name
GPN-loop GTPase 2provided by HGNC
Primary source
HGNC:HGNC:25513
See related
Ensembl:ENSG00000142751
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATPBD1B
Expression
Ubiquitous expression in spleen (RPKM 6.7), duodenum (RPKM 6.2) and 25 other tissues See more
Orthologs

Genomic context

See GPN2 in Genome Data Viewer
Location:
1p36.11
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (26876132..26890283, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (27205872..27216869, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 18 Neighboring gene stratifin Neighboring gene G-patch domain containing 3 Neighboring gene nuclear distribution C, dynein complex regulator Neighboring gene nuclear receptor subfamily 0 group B member 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10349

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
GPN-loop GTPase 2
Names
ATP-binding domain 1 family member B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018066.4NP_060536.3  GPN-loop GTPase 2

    See identical proteins and their annotated locations for NP_060536.3

    Status: VALIDATED

    Source sequence(s)
    AK001211, AL034380, BC007815
    Consensus CDS
    CCDS289.1
    UniProtKB/Swiss-Prot
    Q9H9Y4
    Related
    ENSP00000363250.3, ENST00000374135.9
    Conserved Domains (2) summary
    COG1100
    Location:13182
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam03029
    Location:14261
    ATP_bind_1; Conserved hypothetical ATP binding protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    26876132..26890283 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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