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LRRN3 leucine rich repeat neuronal 3 [ Homo sapiens (human) ]

Gene ID: 54674, updated on 3-Jun-2018
Official Symbol
LRRN3provided by HGNC
Official Full Name
leucine rich repeat neuronal 3provided by HGNC
Primary source
HGNC:HGNC:17200
See related
Ensembl:ENSG00000173114 Vega:OTTHUMG00000155039
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NLRR3; NLRR-3; FIGLER5
Expression
Biased expression in adrenal (RPKM 13.7), brain (RPKM 11.9) and 12 other tissues See more
Orthologs
See LRRN3 in Genome Data Viewer
Location:
7q31.1
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 7 NC_000007.14 (111091006..111125454)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (110731062..110765510)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375451 Neighboring gene uncharacterized LOC105375450 Neighboring gene uncharacterized LOC105375452 Neighboring gene inner mitochondrial membrane peptidase subunit 2 Neighboring gene argininosuccinate synthase 1 pseudogene Neighboring gene DOCK4 antisense RNA 1 Neighboring gene dedicator of cytokinesis 4

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ11129

Gene Ontology Provided by GOA

Process Evidence Code Pubs
positive regulation of synapse assembly IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
leucine-rich repeat neuronal protein 3
Names
fibronectin type III, immunoglobulin and leucine rich repeat domains 5
leucine-rich repeat protein, neuronal 3
neuronal leucine-rich repeat protein 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099658.1NP_001093128.1  leucine-rich repeat neuronal protein 3 precursor

    See identical proteins and their annotated locations for NP_001093128.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AL442092, AY358280, BC035133, DA494543
    Consensus CDS
    CCDS5754.1
    UniProtKB/Swiss-Prot
    Q9H3W5
    UniProtKB/TrEMBL
    A4D0T1
    Related
    ENSP00000312001.5, OTTHUMP00000207167, ENST00000308478.9, OTTHUMT00000338172
    Conserved Domains (6) summary
    TIGR00864
    Location:341442
    PCC; polycystin cation channel protein
    smart00013
    Location:2872
    LRRNT; Leucine rich repeat N-terminal domain
    COG4886
    Location:75355
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:94117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00041
    Location:526593
    fn3; Fibronectin type III domain
    cl11960
    Location:437513
    Ig; Immunoglobulin domain
  2. NM_001099660.1NP_001093130.1  leucine-rich repeat neuronal protein 3 precursor

    See identical proteins and their annotated locations for NP_001093130.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AK001991, AL442092, AY358280, BC035133, DA494543
    Consensus CDS
    CCDS5754.1
    UniProtKB/Swiss-Prot
    Q9H3W5
    UniProtKB/TrEMBL
    A4D0T1, Q9NUU4
    Related
    ENSP00000397312.1, ENST00000451085.5
    Conserved Domains (6) summary
    TIGR00864
    Location:341442
    PCC; polycystin cation channel protein
    smart00013
    Location:2872
    LRRNT; Leucine rich repeat N-terminal domain
    COG4886
    Location:75355
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:94117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00041
    Location:526593
    fn3; Fibronectin type III domain
    cl11960
    Location:437513
    Ig; Immunoglobulin domain
  3. NM_018334.4NP_060804.3  leucine-rich repeat neuronal protein 3 precursor

    See identical proteins and their annotated locations for NP_060804.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AF134481, AL442092, DA494543, DB095402
    Consensus CDS
    CCDS5754.1
    UniProtKB/Swiss-Prot
    Q9H3W5
    UniProtKB/TrEMBL
    A4D0T1
    Related
    ENSP00000412417.2, OTTHUMP00000207166, ENST00000422987.3, OTTHUMT00000338171
    Conserved Domains (6) summary
    TIGR00864
    Location:341442
    PCC; polycystin cation channel protein
    smart00013
    Location:2872
    LRRNT; Leucine rich repeat N-terminal domain
    COG4886
    Location:75355
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:94117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00041
    Location:526593
    fn3; Fibronectin type III domain
    cl11960
    Location:437513
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p12 Primary Assembly

    Range
    111091006..111125454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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