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Ly6g lymphocyte antigen 6 family member G [ Mus musculus (house mouse) ]

Gene ID: 546644, updated on 21-Apr-2024

Summary

Official Symbol
Ly6gprovided by MGI
Official Full Name
lymphocyte antigen 6 family member Gprovided by MGI
Primary source
MGI:MGI:109440
See related
Ensembl:ENSMUSG00000022582 AllianceGenome:MGI:109440
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gr1; Gr-1; Ly-6G
Summary
Located in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 27.4) and liver E18 (RPKM 5.3) See more
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Genomic context

Location:
15 D3; 15 34.29 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (75027110..75030977)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (75155261..75159128)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene lymphocyte antigen 6 family memberC2 Neighboring gene lymphocyte antigen 6 family member A2 Neighboring gene predicted gene 28117 Neighboring gene lymphocyte antigen 6 family member G2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acetylcholine receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables acetylcholine receptor inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in acetylcholine receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
lymphocyte antigen 6G
Names
ly-6G.1
lymphocyte antigen 6 complex, locus G

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310438.1NP_001297367.1  lymphocyte antigen 6G precursor

    See identical proteins and their annotated locations for NP_001297367.1

    Status: VALIDATED

    Description
    Transcript Variant: Both variants 1and 2 encode the same protein.
    Source sequence(s)
    AC116498
    Consensus CDS
    CCDS79377.1
    UniProtKB/Swiss-Prot
    A0A087WQF5, P35461
    UniProtKB/TrEMBL
    A0A668H4Q1
    Related
    ENSMUSP00000140173.2, ENSMUST00000190262.2
    Conserved Domains (1) summary
    pfam00021
    Location:29105
    UPAR_LY6; u-PAR/Ly-6 domain
  2. NM_001374230.1NP_001361159.1  lymphocyte antigen 6G precursor

    Status: VALIDATED

    Description
    Transcript Variant: Both variants 1and 2 encode the same protein.
    Source sequence(s)
    AC116498
    Consensus CDS
    CCDS79377.1
    UniProtKB/Swiss-Prot
    A0A087WQF5, P35461
    UniProtKB/TrEMBL
    A0A668H4Q1
    Conserved Domains (1) summary
    pfam00021
    Location:29105
    UPAR_LY6; u-PAR/Ly-6 domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    75027110..75030977
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_008531.1: Suppressed sequence

    Description
    NM_008531.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.