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Ppp1r3f protein phosphatase 1, regulatory subunit 3F [ Mus musculus (house mouse) ]

Gene ID: 54646, updated on 30-Apr-2024

Summary

Official Symbol
Ppp1r3fprovided by MGI
Official Full Name
protein phosphatase 1, regulatory subunit 3Fprovided by MGI
Primary source
MGI:MGI:1859617
See related
Ensembl:ENSMUSG00000039556 AllianceGenome:MGI:1859617
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
R3F; RF3; Sfc15; DXImx48e
Summary
Predicted to enable glycogen binding activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to act upstream of or within regulation of glycogen (starch) synthase activity. Predicted to be located in membrane. Predicted to be part of protein phosphatase type 1 complex. Is expressed in left lung and right lung. Orthologous to human PPP1R3F (protein phosphatase 1 regulatory subunit 3F). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 6.3), cortex adult (RPKM 5.4) and 27 other tissues See more
Orthologs
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Genomic context

See Ppp1r3f in Genome Data Viewer
Location:
X A1.1; X 3.4 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (7424815..7440541, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (7558562..7574281, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene kelch-like 21 pseudogene Neighboring gene predicted gene, 23082 Neighboring gene STARR-positive B cell enhancer mm9_chrX:7151387-7151688 Neighboring gene Foxp3 regulating long intergenic noncoding RNA Neighboring gene forkhead box P3 Neighboring gene coiled-coil domain containing 22 Neighboring gene calcium channel, voltage-dependent, alpha 1F subunit

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
protein phosphatase 1 regulatory subunit 3F
Names
protein phosphatase 1, regulatory (inhibitor) subunit 3F

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290574.2NP_001277503.1  protein phosphatase 1 regulatory subunit 3F isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL731793
    Consensus CDS
    CCDS72328.1
    UniProtKB/TrEMBL
    B9EHL3
    Related
    ENSMUSP00000122903.2, ENSMUST00000150787.8
    Conserved Domains (1) summary
    pfam03370
    Location:162282
    CBM_21; Carbohydrate/starch-binding module (family 21)
  2. NM_138605.4NP_613071.3  protein phosphatase 1 regulatory subunit 3F isoform 2

    See identical proteins and their annotated locations for NP_613071.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AL731793
    Consensus CDS
    CCDS29964.2
    UniProtKB/Swiss-Prot
    B1AW09, B1AW10, Q3UGL4, Q6PCL6, Q9JIG4
    UniProtKB/TrEMBL
    B9EHL3
    Related
    ENSMUSP00000111407.4, ENSMUST00000115742.9
    Conserved Domains (1) summary
    pfam03370
    Location:163282
    CBM_21; Carbohydrate/starch-binding module (family 21)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    7424815..7440541 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)