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MAP10 microtubule associated protein 10 [ Homo sapiens (human) ]

Gene ID: 54627, updated on 5-Jan-2022

Summary

Official Symbol
MAP10provided by HGNC
Official Full Name
microtubule associated protein 10provided by HGNC
Primary source
HGNC:HGNC:29265
See related
Ensembl:ENSG00000212916 MIM:618551
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MTR120; KIAA1383
Summary
Enables microtubule binding activity. Involved in microtubule cytoskeleton organization; positive regulation of cytokinesis; and regulation of microtubule-based process. Located in microtubule cytoskeleton and midbody. [provided by Alliance of Genome Resources, Nov 2021]
Orthologs
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Genomic context

See MAP10 in Genome Data Viewer
Location:
1q42.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (232805416..232809929)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (232941162..232945675)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1745 Neighboring gene uncharacterized LOC107983960 Neighboring gene long intergenic non-protein coding RNA 1744 Neighboring gene uncharacterized LOC101927711 Neighboring gene RNA, U1 small nuclear 74, pseudogene Neighboring gene uncharacterized LOC105373201

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ75125, KIAA1383, MGC126467

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables microtubule binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in cytoplasmic microtubule organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cytoplasmic microtubule organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitotic spindle midzone assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic spindle midzone assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of microtubule-based process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasmic microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasmic microtubule IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in midbody IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in midbody IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in mitotic spindle midzone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitotic spindle midzone IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in mitotic spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitotic spindle pole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
microtubule-associated protein 10
Names
microtubule regulator 120 KDa
microtubule regulator of 120 KDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019090.3NP_061963.3  microtubule-associated protein 10

    Status: VALIDATED

    Source sequence(s)
    AL451083
    Consensus CDS
    CCDS44334.1
    Related
    ENSP00000403208.2, ENST00000418460.4
    Conserved Domains (2) summary
    pfam14924
    Location:86188
    DUF4497; Protein of unknown function (DUF4497)
    pfam14925
    Location:273904
    HPHLAWLY; Domain of unknown function

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    232805416..232809929
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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