Format

Send to:

Choose Destination

VSIG10 V-set and immunoglobulin domain containing 10 [ Homo sapiens (human) ]

Gene ID: 54621, updated on 17-Jun-2019

Summary

Official Symbol
VSIG10provided by HGNC
Official Full Name
V-set and immunoglobulin domain containing 10provided by HGNC
Primary source
HGNC:HGNC:26078
See related
Ensembl:ENSG00000176834
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in small intestine (RPKM 12.6), colon (RPKM 8.8) and 24 other tissues See more
Orthologs

Genomic context

See VSIG10 in Genome Data Viewer
Location:
12q24.23
Exon count:
11
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (118063593..118104402, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (118501398..118541810, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene kinase suppressor of ras 2 Neighboring gene uncharacterized LOC105370011 Neighboring gene replication factor C subunit 5 Neighboring gene WD repeat and SOCS box containing 2 Neighboring gene uncharacterized LOC101928274 Neighboring gene Sharpr-MPRA regulatory region 576 Neighboring gene phosphatidylethanolamine binding protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog
TAOK3, a novel genome-wide association study locus associated with morphine requirement and postoperative pain in a retrospective pediatric day surgery population.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC1013, FLJ20674

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
V-set and immunoglobulin domain-containing protein 10

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019086.6NP_061959.2  V-set and immunoglobulin domain-containing protein 10 precursor

    See identical proteins and their annotated locations for NP_061959.2

    Status: VALIDATED

    Source sequence(s)
    AC026366, AC131238, BC034471, DA995625
    Consensus CDS
    CCDS44992.1
    UniProtKB/Swiss-Prot
    Q8N0Z9
    Related
    ENSP00000352172.5, ENST00000359236.10
    Conserved Domains (4) summary
    cd00096
    Location:327402
    Ig; Immunoglobulin domain
    smart00410
    Location:31119
    IG_like; Immunoglobulin like
    pfam00047
    Location:136208
    ig; Immunoglobulin domain
    pfam07686
    Location:29119
    V-set; Immunoglobulin V-set domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    118063593..118104402 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019505.1XP_016874994.1  V-set and immunoglobulin domain-containing protein 10 isoform X3

    Conserved Domains (2) summary
    cd00096
    Location:155230
    Ig; Immunoglobulin domain
    smart00410
    Location:152233
    IG_like; Immunoglobulin like
  2. XM_006719467.2XP_006719530.1  V-set and immunoglobulin domain-containing protein 10 isoform X2

    Conserved Domains (3) summary
    cd00096
    Location:226301
    Ig; Immunoglobulin domain
    smart00410
    Location:31119
    IG_like; Immunoglobulin like
    pfam07686
    Location:29119
    V-set; Immunoglobulin V-set domain
  3. XM_011538502.1XP_011536804.1  V-set and immunoglobulin domain-containing protein 10 isoform X1

    Conserved Domains (4) summary
    cd00096
    Location:327402
    Ig; Immunoglobulin domain
    smart00410
    Location:31119
    IG_like; Immunoglobulin like
    pfam00047
    Location:136208
    ig; Immunoglobulin domain
    pfam07686
    Location:29119
    V-set; Immunoglobulin V-set domain
  4. XM_017019504.1XP_016874993.1  V-set and immunoglobulin domain-containing protein 10 isoform X3

    Conserved Domains (2) summary
    cd00096
    Location:155230
    Ig; Immunoglobulin domain
    smart00410
    Location:152233
    IG_like; Immunoglobulin like
  5. XM_017019506.1XP_016874995.1  V-set and immunoglobulin domain-containing protein 10 isoform X4

    Conserved Domains (2) summary
    cd00096
    Location:94169
    Ig; Immunoglobulin domain
    smart00410
    Location:91172
    IG_like; Immunoglobulin like
  6. XM_005253908.4XP_005253965.1  V-set and immunoglobulin domain-containing protein 10 isoform X3

    Conserved Domains (2) summary
    cd00096
    Location:155230
    Ig; Immunoglobulin domain
    smart00410
    Location:152233
    IG_like; Immunoglobulin like
  7. XM_006719468.2XP_006719531.1  V-set and immunoglobulin domain-containing protein 10 isoform X4

    Conserved Domains (2) summary
    cd00096
    Location:94169
    Ig; Immunoglobulin domain
    smart00410
    Location:91172
    IG_like; Immunoglobulin like

RNA

  1. XR_944592.1 RNA Sequence

  2. XR_002957341.1 RNA Sequence

  3. XR_002957343.1 RNA Sequence

  4. XR_002957342.1 RNA Sequence

Support Center