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Pierce2 piercer of microtubule wall 2 [ Mus musculus (house mouse) ]

Gene ID: 546143, updated on 14-Feb-2023

Summary

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Official Symbol
Pierce2provided by MGI
Official Full Name
piercer of microtubule wall 2provided by MGI
Primary source
MGI:MGI:3648770
See related
Ensembl:ENSMUSG00000086158 AllianceGenome:MGI:3648770
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm5918; Ccpg1os; EG546143
Summary
Is expressed in embryo and node. Orthologous to human C15orf65 (chromosome 15 open reading frame 65). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 64.7), kidney adult (RPKM 7.3) and 7 other tissues See more
Orthologs
human all
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Genomic context

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See Pierce2 in Genome Data Viewer
Location:
9; 9 D
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (72886999..72892658, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (72979724..72985376, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene pygopus 1 Neighboring gene dynein axonemal assembly factor 4 Neighboring gene predicted gene, 23567 Neighboring gene cell cycle progression 1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class B Neighboring gene Pigb opposite strand 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. De novo identification of mammalian ciliary motility proteins using cryo-EM. Gui M, et al. Cell, 2021 Nov 11. PMID 34715025, Free PMC Article
  2. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in axoneme assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in biological_process ND
No biological Data available
more info
  
involved_in cilium movement IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in determination of left/right symmetry IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
piercer of microtubule wall 2 protein; uncharacterized protein C15orf65 homolog
Names
cell cycle progression 1, opposite strand

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198789.1 → NP_001185718.1  piercer of microtubule wall 2 protein

    See identical proteins and their annotated locations for NP_001185718.1

    Status: VALIDATED

    Source sequence(s)
    AC158997, AW125236, BC048630
    Consensus CDS
    CCDS72276.1
    UniProtKB/Swiss-Prot
    V9GXK1
    UniProtKB/TrEMBL
    V9GXK1
    Related
    ENSMUSP00000139187.2, ENSMUST00000124565.4
    Conserved Domains (1) summary
    pfam14892
    Location:59 → 110
    DUF4490; Domain of unknown function (DUF4490)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    72886999..72892658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155122.1 → XP_036011015.1  uncharacterized protein C15orf65 homolog isoform X2

    Related
    ENSMUSP00000159587.1, ENSMUST00000249120.1
    Conserved Domains (1) summary
    pfam14892
    Location:39 → 90
    DUF4490; Domain of unknown function (DUF4490)

  2. XM_036155121.1 → XP_036011014.1  uncharacterized protein C15orf65 homolog isoform X1

    Conserved Domains (1) summary
    pfam14892
    Location:71 → 122
    DUF4490; Domain of unknown function (DUF4490)

  3. XM_036155123.1 → XP_036011016.1  uncharacterized protein C15orf65 homolog isoform X2

    Conserved Domains (1) summary
    pfam14892
    Location:39 → 90
    DUF4490; Domain of unknown function (DUF4490)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
V9GXK1.1 GenPept UniProtKB/Swiss-Prot:V9GXK1

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