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L1TD1 LINE1 type transposase domain containing 1 [ Homo sapiens (human) ]

Gene ID: 54596, updated on 7-Dec-2018

Summary

Official Symbol
L1TD1provided by HGNC
Official Full Name
LINE1 type transposase domain containing 1provided by HGNC
Primary source
HGNC:HGNC:25595
See related
Ensembl:ENSG00000240563
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ECAT11
Expression
Biased expression in placenta (RPKM 6.2), testis (RPKM 4.7) and 4 other tissues See more
Orthologs

Genomic context

See L1TD1 in Genome Data Viewer
Location:
1p31.3
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 1 NC_000001.11 (62194802..62212328)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (62660474..62678000)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15a pseudogene 7 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class P pseudogene 2 Neighboring gene KN motif and ankyrin repeat domains 4 Neighboring gene RNA, U6 small nuclear 371, pseudogene Neighboring gene uncharacterized LOC105378768

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10884, MGC133253

Gene Ontology Provided by GOA

Function Evidence Code Pubs
single-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
transposition, RNA-mediated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
LINE-1 type transposase domain-containing protein 1
Names
ES cell-associated protein 11
LINE-1 type transposase domain containing 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164835.1NP_001158307.1  LINE-1 type transposase domain-containing protein 1

    See identical proteins and their annotated locations for NP_001158307.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AB211065, AK001973, BU677875, BX382228, CN428323, CX166941, CX167172, DR005055
    Consensus CDS
    CCDS619.1
    UniProtKB/Swiss-Prot
    Q5T7N2
    Conserved Domains (1) summary
    pfam02994
    Location:600863
    Transposase_22; L1 transposable element
  2. NM_019079.5NP_061952.3  LINE-1 type transposase domain-containing protein 1

    See identical proteins and their annotated locations for NP_061952.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AB211065, AK001973, BU677875, BX382228, CN428323, CX167172, DR005055
    Consensus CDS
    CCDS619.1
    UniProtKB/Swiss-Prot
    Q5T7N2
    Related
    ENSP00000419901.1, ENST00000498273.1
    Conserved Domains (1) summary
    pfam02994
    Location:600863
    Transposase_22; L1 transposable element

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p12 Primary Assembly

    Range
    62194802..62212328
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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