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Tubb1 tubulin, beta 1 class VI [ Mus musculus (house mouse) ]

Gene ID: 545486, updated on 12-Mar-2019

Summary

Official Symbol
Tubb1provided by MGI
Official Full Name
tubulin, beta 1 class VIprovided by MGI
Primary source
MGI:MGI:107814
See related
Ensembl:ENSMUSG00000016255
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
M(beta)1; 2810484G07Rik
Expression
Biased expression in spleen adult (RPKM 21.1), liver E14 (RPKM 14.7) and 6 other tissues See more
Orthologs

Genomic context

See Tubb1 in Genome Data Viewer
Location:
2; 2 H4
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (174450595..174458380)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (174276196..174283383)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene negative elongation factor complex member C/D, Th1l Neighboring gene cathepsin Z Neighboring gene ribosomal protein L30, pseudogene 5 Neighboring gene ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit Neighboring gene PRELI domain containing 3B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

  • Gap junction, organism-specific biosystem (from KEGG)
    Gap junction, organism-specific biosystemGap junctions contain intercellular channels that allow direct communication between the cytosolic compartments of adjacent cells. Each gap junction channel is formed by docking of two 'hemichannels'...
  • Gap junction, conserved biosystem (from KEGG)
    Gap junction, conserved biosystemGap junctions contain intercellular channels that allow direct communication between the cytosolic compartments of adjacent cells. Each gap junction channel is formed by docking of two 'hemichannels'...
  • Phagosome, organism-specific biosystem (from KEGG)
    Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Phagosome, conserved biosystem (from KEGG)
    Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
structural constituent of cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
structural constituent of cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule-based process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule-based process IDA
Inferred from Direct Assay
more info
PubMed 
mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle assembly IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080971.2NP_001074440.1  tubulin beta-1 chain

    See identical proteins and their annotated locations for NP_001074440.1

    Status: VALIDATED

    Source sequence(s)
    AL844534
    Consensus CDS
    CCDS38359.1
    UniProtKB/Swiss-Prot
    A2AQ07
    Related
    ENSMUSP00000016399.5, ENSMUST00000016399.5
    Conserved Domains (2) summary
    PTZ00010
    Location:1428
    PTZ00010; tubulin beta chain; Provisional
    cd02187
    Location:2426
    beta_tubulin; The beta-tubulin family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

    Range
    174450595..174458380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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