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Sh2d1b2 SH2 domain containing 1B2 [ Mus musculus (house mouse) ]

Gene ID: 545378, updated on 13-Mar-2020

Summary

Official Symbol
Sh2d1b2provided by MGI
Official Full Name
SH2 domain containing 1B2provided by MGI
Primary source
MGI:MGI:3622649
See related
Ensembl:ENSMUSG00000073494
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ert; Eat2b; EAT-2B; Sh2d1c
Expression
Biased expression in lung adult (RPKM 1.3), spleen adult (RPKM 0.9) and 8 other tissues See more

Genomic context

See Sh2d1b2 in Genome Data Viewer
Location:
1; 1 H3
Exon count:
4
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (170232871..170251587)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (172163002..172181718)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene UDP-N-acetylglucosamine pyrophosphorylase 1 Neighboring gene U2AF homology motif (UHM) kinase 1 Neighboring gene predicted gene 6345 Neighboring gene SH2 domain containing 1B1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
immune system process IEA
Inferred from Electronic Annotation
more info
 
innate immune response IEA
Inferred from Electronic Annotation
more info
 
negative regulation of natural killer cell mediated cytotoxicity IMP
Inferred from Mutant Phenotype
more info
PubMed 
peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of natural killer cell mediated cytotoxicity IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
regulation of natural killer cell activation IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
SH2 domain-containing protein 1B2
Names
EAT-2-related transducer
SH2 domain protein 1B2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033499.1NP_001028671.1  SH2 domain-containing protein 1B2

    See identical proteins and their annotated locations for NP_001028671.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ140178
    Consensus CDS
    CCDS15469.1
    UniProtKB/Swiss-Prot
    Q45HK4
    Related
    ENSMUSP00000125121.1, ENSMUST00000162752.1
    Conserved Domains (1) summary
    cd10342
    Location:1103
    SH2_SAP1; Src homology 2 (SH2) domain found in SLAM-associated protein (SAP)1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p6 C57BL/6J

    Range
    170232871..170251587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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