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PRMT7 protein arginine methyltransferase 7 [ Homo sapiens (human) ]

Gene ID: 54496, updated on 23-Nov-2023

Summary

Official Symbol
PRMT7provided by HGNC
Official Full Name
protein arginine methyltransferase 7provided by HGNC
Primary source
HGNC:HGNC:25557
See related
Ensembl:ENSG00000132600 MIM:610087; AllianceGenome:HGNC:25557
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SBIDDS
Summary
This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients. [provided by RefSeq, May 2017]
Expression
Ubiquitous expression in small intestine (RPKM 5.3), testis (RPKM 5.1) and 25 other tissues See more
Orthologs
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Genomic context

See PRMT7 in Genome Data Viewer
Location:
16q22.1
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (68311019..68360870)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (74106797..74156712)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (68344922..68392487)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene solute carrier family 7 member 6 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11010 Neighboring gene Sharpr-MPRA regulatory region 6227 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11011 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11012 Neighboring gene RNA, U6 small nuclear 1262, pseudogene Neighboring gene Sharpr-MPRA regulatory region 7703 Neighboring gene solute carrier family 7 member 6 opposite strand Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:68343854-68344818 Neighboring gene small nucleolar RNA U13 Neighboring gene RNA, U4 small nuclear 30, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:68382607-68383107 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11013 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68396471-68397283 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68397284-68398095 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68400892-68401445 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68401446-68401998 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11014 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11015 Neighboring gene sphingomyelin phosphodiesterase 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68413436-68413938 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68413939-68414439 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68415806-68416642 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68416643-68417477 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68422765-68423592 Neighboring gene Sharpr-MPRA regulatory region 9240 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68431713-68432213 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:68432795-68433424 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:68433425-68434052 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:68442570-68443549 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:68444678-68445630 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:68445631-68446581 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7646 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11016 Neighboring gene uncharacterized LOC124903705 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:68504627-68505126 Neighboring gene ribosomal protein L35a pseudogene 33

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Short stature-brachydactyly-obesity-global developmental delay syndrome
MedGen: C4310689 OMIM: 617157 GeneReviews: Not available
Compare labs

EBI GWAS Catalog

Description
Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ10640, KIAA1933

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in genomic imprinting ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in peptidyl-arginine methylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-arginine methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of protein binding IC
Inferred by Curator
more info
PubMed 
involved_in spliceosomal snRNP assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in fibrillar center IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein arginine N-methyltransferase 7
Names
[Myelin basic protein]-arginine N-methyltransferase PRMT7
histone-arginine N-methyltransferase PRMT7
NP_001171753.1
NP_001276947.1
NP_001338072.1
NP_001338073.1
NP_001364947.1
NP_001364949.1
NP_001364950.1
NP_001364951.1
NP_001364952.1
NP_061896.1
XP_011521414.1
XP_011521415.1
XP_011521417.1
XP_011521418.1
XP_011521423.1
XP_016878781.1
XP_016878785.1
XP_016878786.1
XP_016878787.1
XP_016878788.1
XP_016878789.1
XP_016878790.1
XP_016878793.1
XP_047290173.1
XP_047290174.1
XP_047290175.1
XP_047290176.1
XP_047290177.1
XP_047290178.1
XP_047290179.1
XP_047290180.1
XP_047290181.1
XP_047290182.1
XP_047290183.1
XP_047290184.1
XP_047290185.1
XP_047290186.1
XP_047290187.1
XP_047290188.1
XP_047290189.1
XP_047290190.1
XP_047290191.1
XP_047290192.1
XP_047290193.1
XP_047290194.1
XP_047290195.1
XP_054236454.1
XP_054236455.1
XP_054236456.1
XP_054236457.1
XP_054236458.1
XP_054236459.1
XP_054236460.1
XP_054236461.1
XP_054236462.1
XP_054236463.1
XP_054236464.1
XP_054236465.1
XP_054236466.1
XP_054236467.1
XP_054236468.1
XP_054236469.1
XP_054236470.1
XP_054236471.1
XP_054236472.1
XP_054236473.1
XP_054236474.1
XP_054236475.1
XP_054236476.1
XP_054236477.1
XP_054236478.1
XP_054236479.1
XP_054236480.1
XP_054236481.1
XP_054236482.1
XP_054236483.1
XP_054236484.1
XP_054236485.1
XP_054236486.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054896.2 RefSeqGene

    Range
    5002..52567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184824.4NP_001171753.1  protein arginine N-methyltransferase 7 isoform 2

    See identical proteins and their annotated locations for NP_001171753.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks an exon in the 5' coding region, and its 3' terminal exon extends past a splice site that is used in variant 4, which results in a novel 3' coding region and 3' UTR compared to variant 4. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 4.
    Source sequence(s)
    AC099521, AK304605, CB140365, DA648148
    Consensus CDS
    CCDS54033.1
    UniProtKB/TrEMBL
    A0A8I5QKZ3
    Related
    ENSP00000414716.3, ENST00000449359.7
  2. NM_001290018.2NP_001276947.1  protein arginine N-methyltransferase 7 isoform 1

    See identical proteins and their annotated locations for NP_001276947.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and its 3' terminal exon extends past a splice site that is used in variant 4, which results in a novel 3' coding region and 3' UTR compared to variant 4. The encoded isoform (1) is shorter and has a distinct C-terminus compared to isoform 4. Both variants 1 and 3 encode the same isoform (1).
    Source sequence(s)
    AC020978, AC099521, AK056647, AK304605, CB140365
    Consensus CDS
    CCDS10866.1
    UniProtKB/Swiss-Prot
    B3KPR0, B3KUG9, B4E379, Q96PV5, Q9H9L0, Q9NVM4
    UniProtKB/TrEMBL
    H3BRD3
    Related
    ENSP00000343103.5, ENST00000339507.9
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  3. NM_001351143.3NP_001338072.1  protein arginine N-methyltransferase 7 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) encodes the longest isoform (4).
    Source sequence(s)
    AC020978, AC099521
    Consensus CDS
    CCDS92187.1
    UniProtKB/TrEMBL
    A0A8I5KYD6, H3BRD3
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  4. NM_001351144.3NP_001338073.1  protein arginine N-methyltransferase 7 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) uses two alternate in-frame splice sites and its 3' terminal exon extends past a splice site that is used in variant 4, which results in a novel 3' coding region and 3' UTR compared to variant 4. The encoded isoform (5) is shorter and has a distinct C-terminus compared to isoform 4.
    Source sequence(s)
    AC020978, AC099521, CB140365
    Consensus CDS
    CCDS92184.1
    UniProtKB/TrEMBL
    A0A8I5KZ92, H3BRD3
    Related
    ENSP00000510669.1, ENST00000692632.1
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  5. NM_001378018.1NP_001364947.1  protein arginine N-methyltransferase 7 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
    Consensus CDS
    CCDS10866.1
    UniProtKB/Swiss-Prot
    B3KPR0, B3KUG9, B4E379, Q96PV5, Q9H9L0, Q9NVM4
    UniProtKB/TrEMBL
    H3BRD3
    Related
    ENSP00000510748.1, ENST00000692760.1
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  6. NM_001378020.1NP_001364949.1  protein arginine N-methyltransferase 7 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
    UniProtKB/TrEMBL
    A0A8I5QKZ3
  7. NM_001378021.1NP_001364950.1  protein arginine N-methyltransferase 7 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
    UniProtKB/TrEMBL
    A0A8I5QKZ3
    Related
    ENSP00000510167.1, ENST00000691663.1
  8. NM_001378022.1NP_001364951.1  protein arginine N-methyltransferase 7 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
    UniProtKB/TrEMBL
    A0A8I5QKZ3
  9. NM_001378023.1NP_001364952.1  protein arginine N-methyltransferase 7 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
    UniProtKB/TrEMBL
    A0A8I5QKZ3
  10. NM_019023.5NP_061896.1  protein arginine N-methyltransferase 7 isoform 1

    See identical proteins and their annotated locations for NP_061896.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) includes a 3' terminal exon that extends past a splice site that is used in variant 4, which results in a novel 3' coding region and 3' UTR compared to variant 4. The encoded isoform (1) is shorter and has a distinct C-terminus compared to isoform 4. Both variants 1 and 3 encode the same isoform (1).
    Source sequence(s)
    AC020978, AC099521, AK001502, AK022739, DB150163
    Consensus CDS
    CCDS10866.1
    UniProtKB/Swiss-Prot
    B3KPR0, B3KUG9, B4E379, Q96PV5, Q9H9L0, Q9NVM4
    UniProtKB/TrEMBL
    H3BRD3
    Related
    ENSP00000409324.2, ENST00000441236.3
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RNA

  1. NR_147056.3 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks two exons and uses two alternate splice sites compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC020978, AC099521, CB140365
  2. NR_147057.3 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) contains an alternate exon, lacks an exon, and uses two alternate splice sites compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC020978, AC099521, CB140365
  3. NR_147058.3 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) lacks an exon and uses two alternate splice sites compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC020978, AC099521, CB140365
    Related
    ENST00000688969.1
  4. NR_165365.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
  5. NR_165366.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
    Related
    ENST00000688470.1
  6. NR_165367.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
  7. NR_165368.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
  8. NR_165369.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
  9. NR_165370.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
  10. NR_165371.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
  11. NR_165372.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521
    Related
    ENST00000675132.1
  12. NR_165373.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC020978, AC099521

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    68311019..68360870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047434220.1XP_047290176.1  protein arginine N-methyltransferase 7 isoform X5

    UniProtKB/TrEMBL
    A0A8I5KXS9, H3BRD3
  2. XM_047434222.1XP_047290178.1  protein arginine N-methyltransferase 7 isoform X5

    UniProtKB/TrEMBL
    A0A8I5KXS9, H3BRD3
  3. XM_017023297.3XP_016878786.1  protein arginine N-methyltransferase 7 isoform X5

    UniProtKB/TrEMBL
    A0A8I5KXS9, H3BRD3
    Related
    ENSP00000510630.1, ENST00000686904.1
  4. XM_017023296.3XP_016878785.1  protein arginine N-methyltransferase 7 isoform X4

    UniProtKB/TrEMBL
    H3BRD3
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  5. XM_047434221.1XP_047290177.1  protein arginine N-methyltransferase 7 isoform X5

    UniProtKB/TrEMBL
    A0A8I5KXS9, H3BRD3
  6. XM_047434218.1XP_047290174.1  protein arginine N-methyltransferase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8I5KYD6, H3BRD3
    Related
    ENSP00000509677.1, ENST00000687654.1
  7. XM_047434217.1XP_047290173.1  protein arginine N-methyltransferase 7 isoform X1

    UniProtKB/TrEMBL
    H3BRD3
  8. XM_017023292.3XP_016878781.1  protein arginine N-methyltransferase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8I5KYD6, H3BRD3
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  9. XM_011523115.4XP_011521417.1  protein arginine N-methyltransferase 7 isoform X1

    See identical proteins and their annotated locations for XP_011521417.1

    UniProtKB/TrEMBL
    H3BRD3
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  10. XM_047434224.1XP_047290180.1  protein arginine N-methyltransferase 7 isoform X8

    UniProtKB/TrEMBL
    A0A8I5KPT4
  11. XM_047434229.1XP_047290185.1  protein arginine N-methyltransferase 7 isoform X12

    UniProtKB/TrEMBL
    A0A8I5KPT4
  12. XM_047434226.1XP_047290182.1  protein arginine N-methyltransferase 7 isoform X9

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  13. XM_011523113.4XP_011521415.1  protein arginine N-methyltransferase 7 isoform X1

    See identical proteins and their annotated locations for XP_011521415.1

    UniProtKB/TrEMBL
    H3BRD3
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  14. XM_017023299.3XP_016878788.1  protein arginine N-methyltransferase 7 isoform X8

    UniProtKB/TrEMBL
    A0A8I5KPT4
    Related
    ENSP00000510574.1, ENST00000691961.1
  15. XM_017023298.3XP_016878787.1  protein arginine N-methyltransferase 7 isoform X6

    UniProtKB/TrEMBL
    A0A8I5KPT4
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  16. XM_017023301.3XP_016878790.1  protein arginine N-methyltransferase 7 isoform X12

    UniProtKB/TrEMBL
    A0A8I5KPT4
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  17. XM_017023300.3XP_016878789.1  protein arginine N-methyltransferase 7 isoform X11

    UniProtKB/TrEMBL
    A0A8I5KPT4
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  18. XM_047434227.1XP_047290183.1  protein arginine N-methyltransferase 7 isoform X10

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  19. XM_047434225.1XP_047290181.1  protein arginine N-methyltransferase 7 isoform X9

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  20. XM_047434234.1XP_047290190.1  protein arginine N-methyltransferase 7 isoform X17

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  21. XM_011523116.4XP_011521418.1  protein arginine N-methyltransferase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8I5KYD6, H3BRD3
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  22. XM_047434219.1XP_047290175.1  protein arginine N-methyltransferase 7 isoform X3

    UniProtKB/TrEMBL
    A0A8I5KZ92, H3BRD3
  23. XM_011523112.4XP_011521414.1  protein arginine N-methyltransferase 7 isoform X1

    See identical proteins and their annotated locations for XP_011521414.1

    UniProtKB/TrEMBL
    H3BRD3
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  24. XM_047434223.1XP_047290179.1  protein arginine N-methyltransferase 7 isoform X7

    UniProtKB/TrEMBL
    A0A8I5KPT4
  25. XM_047434228.1XP_047290184.1  protein arginine N-methyltransferase 7 isoform X12

    UniProtKB/TrEMBL
    A0A8I5KPT4
  26. XM_011523121.4XP_011521423.1  protein arginine N-methyltransferase 7 isoform X9

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  27. XM_047434235.1XP_047290191.1  protein arginine N-methyltransferase 7 isoform X17

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  28. XM_017023304.3XP_016878793.1  protein arginine N-methyltransferase 7 isoform X14

    UniProtKB/TrEMBL
    A0A6Q8PFP4
    Conserved Domains (1) summary
    cl17173
    Location:37186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  29. XM_047434231.1XP_047290187.1  protein arginine N-methyltransferase 7 isoform X15

    UniProtKB/TrEMBL
    A0A8I5KRV0, H3BNC0, H3BTY1
    Related
    ENSP00000510428.1, ENST00000692966.1
  30. XM_047434232.1XP_047290188.1  protein arginine N-methyltransferase 7 isoform X15

    UniProtKB/TrEMBL
    A0A8I5KRV0, H3BNC0, H3BTY1
    Related
    ENSP00000454776.1, ENST00000568975.5
  31. XM_047434238.1XP_047290194.1  protein arginine N-methyltransferase 7 isoform X20

    UniProtKB/TrEMBL
    A0A8I5KRV0
  32. XM_047434236.1XP_047290192.1  protein arginine N-methyltransferase 7 isoform X18

    UniProtKB/TrEMBL
    A0A8I5KRV0
  33. XM_047434237.1XP_047290193.1  protein arginine N-methyltransferase 7 isoform X19

    UniProtKB/TrEMBL
    A0A8I5KPP4, A0A8I5KRA7
    Related
    ENSP00000509231.1, ENST00000692621.1
  34. XM_047434233.1XP_047290189.1  protein arginine N-methyltransferase 7 isoform X16

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  35. XM_047434230.1XP_047290186.1  protein arginine N-methyltransferase 7 isoform X13

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  36. XM_047434239.1XP_047290195.1  protein arginine N-methyltransferase 7 isoform X21

RNA

  1. XR_007064885.1 RNA Sequence

  2. XR_001751915.3 RNA Sequence

  3. XR_007064887.1 RNA Sequence

  4. XR_002957814.2 RNA Sequence

  5. XR_007064888.1 RNA Sequence

  6. XR_007064886.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    74106797..74156712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054380487.1XP_054236462.1  protein arginine N-methyltransferase 7 isoform X5

    UniProtKB/TrEMBL
    A0A8I5KXS9, H3BRD3
  2. XM_054380489.1XP_054236464.1  protein arginine N-methyltransferase 7 isoform X5

    UniProtKB/TrEMBL
    A0A8I5KXS9, H3BRD3
  3. XM_054380486.1XP_054236461.1  protein arginine N-methyltransferase 7 isoform X5

    UniProtKB/TrEMBL
    A0A8I5KXS9, H3BRD3
  4. XM_054380485.1XP_054236460.1  protein arginine N-methyltransferase 7 isoform X4

    UniProtKB/TrEMBL
    H3BRD3
  5. XM_054380488.1XP_054236463.1  protein arginine N-methyltransferase 7 isoform X5

    UniProtKB/TrEMBL
    A0A8I5KXS9, H3BRD3
  6. XM_054380492.1XP_054236467.1  protein arginine N-methyltransferase 7 isoform X8

    UniProtKB/TrEMBL
    A0A8I5KPT4
  7. XM_054380496.1XP_054236471.1  protein arginine N-methyltransferase 7 isoform X12

    UniProtKB/TrEMBL
    A0A8I5KPT4
  8. XM_054380499.1XP_054236474.1  protein arginine N-methyltransferase 7 isoform X23

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  9. XM_054380480.1XP_054236455.1  protein arginine N-methyltransferase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8I5KYD6, H3BRD3
  10. XM_054380494.1XP_054236469.1  protein arginine N-methyltransferase 7 isoform X8

    UniProtKB/TrEMBL
    A0A8I5KPT4
  11. XM_054380498.1XP_054236473.1  protein arginine N-methyltransferase 7 isoform X12

    UniProtKB/TrEMBL
    A0A8I5KPT4
  12. XM_054380491.1XP_054236466.1  protein arginine N-methyltransferase 7 isoform X8

    UniProtKB/TrEMBL
    A0A8I5KPT4
  13. XM_054380495.1XP_054236470.1  protein arginine N-methyltransferase 7 isoform X12

    UniProtKB/TrEMBL
    A0A8I5KPT4
  14. XM_054380500.1XP_054236475.1  protein arginine N-methyltransferase 7 isoform X24

    UniProtKB/TrEMBL
    A0A8I5KPT4
  15. XM_054380506.1XP_054236481.1  protein arginine N-methyltransferase 7 isoform X17

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  16. XM_054380483.1XP_054236458.1  protein arginine N-methyltransferase 7 isoform X3

    UniProtKB/TrEMBL
    A0A8I5KZ92, H3BRD3
  17. XM_054380479.1XP_054236454.1  protein arginine N-methyltransferase 7 isoform X1

    UniProtKB/TrEMBL
    H3BRD3
  18. XM_054380490.1XP_054236465.1  protein arginine N-methyltransferase 7 isoform X7

    UniProtKB/TrEMBL
    A0A8I5KPT4
  19. XM_054380497.1XP_054236472.1  protein arginine N-methyltransferase 7 isoform X12

    UniProtKB/TrEMBL
    A0A8I5KPT4
  20. XM_054380507.1XP_054236482.1  protein arginine N-methyltransferase 7 isoform X17

    UniProtKB/TrEMBL
    A0A8I5QKZ3
  21. XM_054380503.1XP_054236478.1  protein arginine N-methyltransferase 7 isoform X15

    UniProtKB/TrEMBL
    A0A8I5KRV0
  22. XM_054380504.1XP_054236479.1  protein arginine N-methyltransferase 7 isoform X15

    UniProtKB/TrEMBL
    A0A8I5KRV0
  23. XM_054380505.1XP_054236480.1  protein arginine N-methyltransferase 7 isoform X15

    UniProtKB/TrEMBL
    A0A8I5KRV0
  24. XM_054380502.1XP_054236477.1  protein arginine N-methyltransferase 7 isoform X26

    UniProtKB/TrEMBL
    A0A8I5KQA6
  25. XM_054380511.1XP_054236486.1  protein arginine N-methyltransferase 7 isoform X20

    UniProtKB/TrEMBL
    A0A8I5KRV0
  26. XM_054380508.1XP_054236483.1  protein arginine N-methyltransferase 7 isoform X18

    UniProtKB/TrEMBL
    A0A8I5KRV0
  27. XM_054380509.1XP_054236484.1  protein arginine N-methyltransferase 7 isoform X19

    UniProtKB/TrEMBL
    A0A8I5KPP4, A0A8I5KRA7
  28. XM_054380510.1XP_054236485.1  protein arginine N-methyltransferase 7 isoform X19

    UniProtKB/TrEMBL
    A0A8I5KPP4, A0A8I5KRA7
  29. XM_054380481.1XP_054236456.1  protein arginine N-methyltransferase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8I5KYD6, H3BRD3
  30. XM_054380482.1XP_054236457.1  protein arginine N-methyltransferase 7 isoform X3

    UniProtKB/TrEMBL
    A0A8I5KZ92, H3BRD3
  31. XM_054380493.1XP_054236468.1  protein arginine N-methyltransferase 7 isoform X8

    UniProtKB/TrEMBL
    A0A8I5KPT4
  32. XM_054380501.1XP_054236476.1  protein arginine N-methyltransferase 7 isoform X25

    UniProtKB/TrEMBL
    A0A8I5KPT4, A0A8I5KZ05
  33. XM_054380484.1XP_054236459.1  protein arginine N-methyltransferase 7 isoform X22

    UniProtKB/Swiss-Prot
    B3KPR0, B3KUG9, B4E379, Q96PV5, Q9H9L0, Q9NVM4
    UniProtKB/TrEMBL
    H3BRD3

RNA

  1. XR_008489096.1 RNA Sequence

  2. XR_008489095.1 RNA Sequence

  3. XR_008489098.1 RNA Sequence

  4. XR_008489094.1 RNA Sequence

  5. XR_008489099.1 RNA Sequence

  6. XR_008489097.1 RNA Sequence