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PRR13 proline rich 13 [ Homo sapiens (human) ]

Gene ID: 54458, updated on 13-Mar-2020

Summary

Official Symbol
PRR13provided by HGNC
Official Full Name
proline rich 13provided by HGNC
Primary source
HGNC:HGNC:24528
See related
Ensembl:ENSG00000205352 MIM:610459
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TXR1
Expression
Ubiquitous expression in small intestine (RPKM 163.5), duodenum (RPKM 160.5) and 24 other tissues See more
Orthologs

Genomic context

See PRR13 in Genome Data Viewer
Location:
12q13.13
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (53441649..53446643)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (53835433..53840427)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr12.1897 Neighboring gene anti-Mullerian hormone receptor type 2 Neighboring gene poly(rC) binding protein 2 Neighboring gene PCBP2 overlapping transcript 1 Neighboring gene mitogen-activated protein kinase kinase kinase 12 Neighboring gene TARBP2 subunit of RISC loading complex

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23818, FLJ58476, DKFZp564J157

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
proline-rich protein 13
Names
taxane-resistance protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005354.2NP_001005354.1  proline-rich protein 13 isoform 2

    See identical proteins and their annotated locations for NP_001005354.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an in-frame segment in the 5' coding region compared to variant 2. The encoded protein (isoform 2) is shorter than isoform 1.
    Source sequence(s)
    AK074398, BX640962, CN392914
    Consensus CDS
    CCDS31811.1
    UniProtKB/Swiss-Prot
    Q9NZ81
    Related
    ENSP00000369112.4, ENST00000379786.8
  2. NM_018457.4NP_060927.1  proline-rich protein 13 isoform 1

    See identical proteins and their annotated locations for NP_060927.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BC014257, CN392914
    Consensus CDS
    CCDS44899.1
    UniProtKB/Swiss-Prot
    Q9NZ81
    UniProtKB/TrEMBL
    A0A024RB45
    Related
    ENSP00000412064.2, ENST00000429243.7

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    53441649..53446643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001005355.1: Suppressed sequence

    Description
    NM_001005355.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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