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RBM27 RNA binding motif protein 27 [ Homo sapiens (human) ]

Gene ID: 54439, updated on 23-Nov-2021

Summary

Official Symbol
RBM27provided by HGNC
Official Full Name
RNA binding motif protein 27provided by HGNC
Primary source
HGNC:HGNC:29243
See related
Ensembl:ENSG00000091009 Ensembl:ENSG00000275740
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Psc1; ARRS1; ZC3H18; ZC3H20
Expression
Ubiquitous expression in testis (RPKM 10.3), bone marrow (RPKM 8.5) and 25 other tissues See more
Orthologs
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Genomic context

See RBM27 in Genome Data Viewer
Location:
5q32
Exon count:
21
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (146203550..146289223)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (145583168..145668786)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene leucyl-tRNA synthetase 1 Neighboring gene ribosomal protein L35a pseudogene 16 Neighboring gene ribosomal protein L35a pseudogene 17 Neighboring gene RNA, U7 small nuclear 180 pseudogene Neighboring gene POU class 4 homeobox 3 Neighboring gene uncharacterized LOC105378213

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1311

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
RNA-binding protein 27
Names
acidic rich RS domain containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018989.2NP_061862.1  RNA-binding protein 27

    See identical proteins and their annotated locations for NP_061862.1

    Status: VALIDATED

    Source sequence(s)
    AB037732, AL833706, BX647384
    Consensus CDS
    CCDS43378.1
    UniProtKB/Swiss-Prot
    Q9P2N5
    Related
    ENSP00000265271.5, ENST00000265271.7
    Conserved Domains (5) summary
    cd12517
    Location:599674
    RRM_RBM27; RNA recognition motif of vertebrate RNA-binding protein 27 (RBM27)
    pfam00642
    Location:277299
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl02562
    Location:772
    PWI; PWI domain
    cl17169
    Location:9711013
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl19219
    Location:813902
    DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    146203550..146289223
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005268466.1XP_005268523.1  RNA-binding protein 27 isoform X1

    Conserved Domains (5) summary
    cd12517
    Location:600675
    RRM_RBM27; RNA recognition motif of vertebrate RNA-binding protein 27 (RBM27)
    pfam00642
    Location:278300
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl02562
    Location:772
    PWI; PWI domain
    cl17169
    Location:9721014
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl19219
    Location:814903
    DUF342; Protein of unknown function (DUF342)
  2. XM_011537661.1XP_011535963.1  RNA-binding protein 27 isoform X6

    Conserved Domains (4) summary
    pfam00642
    Location:278300
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl02562
    Location:772
    PWI; PWI domain
    cl17169
    Location:600644
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl19219
    Location:715804
    DUF342; Protein of unknown function (DUF342)
  3. XM_005268467.1XP_005268524.1  RNA-binding protein 27 isoform X4

    Conserved Domains (5) summary
    cd12517
    Location:545620
    RRM_RBM27; RNA recognition motif of vertebrate RNA-binding protein 27 (RBM27)
    pfam00642
    Location:278300
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl02562
    Location:772
    PWI; PWI domain
    cl17169
    Location:917959
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl19219
    Location:759848
    DUF342; Protein of unknown function (DUF342)
  4. XM_006714787.1XP_006714850.1  RNA-binding protein 27 isoform X2

    Conserved Domains (5) summary
    cd12517
    Location:588663
    RRM_RBM27; RNA recognition motif of vertebrate RNA-binding protein 27 (RBM27)
    pfam00642
    Location:278300
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl02562
    Location:772
    PWI; PWI domain
    cl17169
    Location:9601002
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl19219
    Location:802891
    DUF342; Protein of unknown function (DUF342)
  5. XM_011537662.1XP_011535964.1  RNA-binding protein 27 isoform X7

    Conserved Domains (4) summary
    pfam00642
    Location:277299
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl02562
    Location:772
    PWI; PWI domain
    cl17169
    Location:599643
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl19219
    Location:714803
    DUF342; Protein of unknown function (DUF342)
  6. XM_005268468.1XP_005268525.1  RNA-binding protein 27 isoform X5

    Related
    ENSP00000475384.1, ENST00000506502.2
    Conserved Domains (5) summary
    cd12517
    Location:544619
    RRM_RBM27; RNA recognition motif of vertebrate RNA-binding protein 27 (RBM27)
    pfam00642
    Location:277299
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    cl02562
    Location:772
    PWI; PWI domain
    cl17169
    Location:916958
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl19219
    Location:758847
    DUF342; Protein of unknown function (DUF342)
  7. XM_017009587.1XP_016865076.1  RNA-binding protein 27 isoform X3

RNA

  1. XR_944325.2 RNA Sequence

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