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TAS2R5 taste 2 receptor member 5 [ Homo sapiens (human) ]

Gene ID: 54429, updated on 22-Sep-2022

Summary

Official Symbol
TAS2R5provided by HGNC
Official Full Name
taste 2 receptor member 5provided by HGNC
Primary source
HGNC:HGNC:14912
See related
Ensembl:ENSG00000127366 MIM:605062; AllianceGenome:HGNC:14912
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T2R5
Summary
This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See TAS2R5 in Genome Data Viewer
Location:
7q34
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (141790217..141791367)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (143106036..143107186)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (141490017..141491167)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene taste 2 receptor member 4 Neighboring gene taste 2 receptor member 6 pseudogene Neighboring gene MT-CO1 pseudogene 55 Neighboring gene MT-ND2 pseudogene 5

Genomic regions, transcripts, and products

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC126635, MGC126637

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables bitter taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables bitter taste receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables taste receptor activity TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IC
Inferred by Curator
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
taste receptor type 2 member 5
Names
taste receptor, type 2, member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018980.3NP_061853.1  taste receptor type 2 member 5

    See identical proteins and their annotated locations for NP_061853.1

    Status: REVIEWED

    Source sequence(s)
    AC004979, AW881072, BC095522
    Consensus CDS
    CCDS5869.1
    UniProtKB/Swiss-Prot
    Q75MV7, Q9NYW4
    UniProtKB/TrEMBL
    A4D1U0, Q502V5
    Related
    ENSP00000247883.4, ENST00000247883.5
    Conserved Domains (1) summary
    pfam05296
    Location:1290
    TAS2R; Taste receptor protein (TAS2R)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    141790217..141791367
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    143106036..143107186
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)