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Bet1l Bet1 golgi vesicular membrane trafficking protein like [ Mus musculus (house mouse) ]

Gene ID: 54399, updated on 5-Mar-2024

Summary

Official Symbol
Bet1lprovided by MGI
Official Full Name
Bet1 golgi vesicular membrane trafficking protein likeprovided by MGI
Primary source
MGI:MGI:1913128
See related
Ensembl:ENSMUSG00000025484 AllianceGenome:MGI:1913128
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gs15; 2610021K23Rik
Summary
Enables SNAP receptor activity. Predicted to be involved in regulation of retrograde vesicle-mediated transport, Golgi to ER and retrograde transport, endosome to Golgi. Located in Golgi membrane and Golgi stack. Human ortholog(s) of this gene implicated in uterine fibroid. Orthologous to human BET1L (Bet1 golgi vesicular membrane trafficking protein like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 17.1), limb E14.5 (RPKM 16.0) and 28 other tissues See more
Orthologs
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Genomic context

See Bet1l in Genome Data Viewer
Location:
7 F4; 7 86.05 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (140433297..140437306, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (140853384..140857156, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA C330022C24 gene Neighboring gene secretoglobin, family 1C, member 1 Neighboring gene ciliary microtubule associated protein 1A Neighboring gene STARR-positive B cell enhancer ABC_E1748 Neighboring gene RIC8 guanine nucleotide exchange factor A Neighboring gene sirtuin 3 Neighboring gene STARR-positive B cell enhancer ABC_E9304 Neighboring gene proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 Neighboring gene DnaJ (Hsp40) homolog, subfamily A, member 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables SNAP receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables SNAP receptor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi stack IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi stack ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi-associated vesicle ISO
Inferred from Sequence Orthology
more info
 
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endosome ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
BET1-like protein
Names
GOS-15
blocked early in transport 1 homolog-like
golgi SNARE with a size of 15 kDa
golgi SNARE, 15 kD
soluble N-ethylmaleimide-sensitive factor attachment protein (SNARE) 15
vesicle transport protein GOS15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018742.5NP_061212.3  BET1-like protein

    See identical proteins and their annotated locations for NP_061212.3

    Status: VALIDATED

    Source sequence(s)
    AK011508, AK161239, BY292666
    Consensus CDS
    CCDS21987.1
    UniProtKB/Swiss-Prot
    O35153, Q9D0E4
    UniProtKB/TrEMBL
    A0A1B0GS34
    Related
    ENSMUSP00000026557.9, ENSMUST00000026557.10
    Conserved Domains (1) summary
    cd15853
    Location:1876
    SNARE_Bet1; SNARE motif of Bet1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    140433297..140437306 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242798.2XP_030098658.1  BET1-like protein isoform X1

    UniProtKB/Swiss-Prot
    O35153, Q9D0E4
    UniProtKB/TrEMBL
    A0A1B0GS34
    Conserved Domains (1) summary
    cd15853
    Location:1876
    SNARE_Bet1; SNARE motif of Bet1