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Cacng4 calcium channel, voltage-dependent, gamma subunit 4 [ Mus musculus (house mouse) ]

Gene ID: 54377, updated on 10-Oct-2019

Summary

Official Symbol
Cacng4provided by MGI
Official Full Name
calcium channel, voltage-dependent, gamma subunit 4provided by MGI
Primary source
MGI:MGI:1859167
See related
Ensembl:ENSMUSG00000020723
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI413107; AW491861
Expression
Biased expression in whole brain E14.5 (RPKM 47.6), CNS E18 (RPKM 44.4) and 7 other tissues See more
Orthologs

Genomic context

See Cacng4 in Genome Data Viewer
Location:
11; 11 E1
Exon count:
4
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (107732357..107794706, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (107596094..107655778, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene helicase with zinc finger domain Neighboring gene microRNA 6932 Neighboring gene VISTA enhancer mm1348 Neighboring gene calcium channel, voltage-dependent, gamma subunit 1 Neighboring gene calcium channel, voltage-dependent, gamma subunit 5 Neighboring gene protein kinase C, alpha Neighboring gene microRNA 7223

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium channel activity IEA
Inferred from Electronic Annotation
more info
 
calcium channel regulator activity ISO
Inferred from Sequence Orthology
more info
 
ionotropic glutamate receptor binding ISO
Inferred from Sequence Orthology
more info
 
voltage-gated calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
voltage-gated ion channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
calcium ion transport IEA
Inferred from Electronic Annotation
more info
 
ion transport IEA
Inferred from Electronic Annotation
more info
 
neurotransmitter receptor internalization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neurotransmitter receptor transport, postsynaptic endosome to lysosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of AMPA receptor activity ISO
Inferred from Sequence Orthology
more info
 
postsynaptic neurotransmitter receptor diffusion trapping IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of AMPA receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of AMPA receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of AMPA receptor activity ISO
Inferred from Sequence Orthology
more info
 
regulation of ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
regulation of postsynaptic neurotransmitter receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
regulation of postsynaptic neurotransmitter receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to cocaine ISO
Inferred from Sequence Orthology
more info
 
transmission of nerve impulse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transmission of nerve impulse IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
AMPA glutamate receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
AMPA glutamate receptor complex IDA
Inferred from Direct Assay
more info
PubMed 
AMPA glutamate receptor complex ISO
Inferred from Sequence Orthology
more info
 
L-type voltage-gated calcium channel complex ISO
Inferred from Sequence Orthology
more info
 
cell body ISO
Inferred from Sequence Orthology
more info
 
cell surface ISO
Inferred from Sequence Orthology
more info
 
glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of postsynaptic density membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
postsynaptic density membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
postsynaptic density membrane ISO
Inferred from Sequence Orthology
more info
 
somatodendritic compartment IDA
Inferred from Direct Assay
more info
PubMed 
voltage-gated calcium channel complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
voltage-dependent calcium channel gamma-4 subunit
Names
TARP gamma-4
neuronal voltage-gated calcium channel gamma-4 subunit
transmembrane AMPAR regulatory protein gamma-4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019431.4NP_062304.1  voltage-dependent calcium channel gamma-4 subunit

    See identical proteins and their annotated locations for NP_062304.1

    Status: VALIDATED

    Source sequence(s)
    AL645853, AL645947
    Consensus CDS
    CCDS25571.1
    UniProtKB/Swiss-Prot
    Q9JJV4
    UniProtKB/TrEMBL
    A2AAU2
    Related
    ENSMUSP00000021066.3, ENSMUST00000021066.3
    Conserved Domains (1) summary
    cl21598
    Location:6202
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p6 C57BL/6J

    Range
    107732357..107794706 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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