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Ctnnal1 catenin alpha like 1 [ Mus musculus (house mouse) ]

Gene ID: 54366, updated on 10-Jun-2024


Official Symbol
Ctnnal1provided by MGI
Official Full Name
catenin alpha like 1provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000038816 AllianceGenome:MGI:1859649
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ACRP; Catnal1
Predicted to enable actin filament binding activity and cadherin binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within Rho protein signal transduction. Predicted to be located in cytosol. Orthologous to human CTNNAL1 (catenin alpha like 1). [provided by Alliance of Genome Resources, Apr 2022]
Broad expression in bladder adult (RPKM 18.0), CNS E11.5 (RPKM 7.9) and 21 other tissues See more
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Genomic context

See Ctnnal1 in Genome Data Viewer
4 B3; 4 31.66 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (56810935..56865370, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (56810935..56865375, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene actin-like 7a Neighboring gene elongator complex protein 1 Neighboring gene actin binding transcription modulator Neighboring gene STARR-seq mESC enhancer starr_10312 Neighboring gene STARR-positive B cell enhancer ABC_E9083 Neighboring gene transmembrane protein 245 Neighboring gene predicted gene, 25053 Neighboring gene microRNA 32

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


GeneRIFs: Gene References Into Functions

What's a GeneRIF?



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Gene trapped (1) 
  • Targeted (3)  1 citation

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
Process Evidence Code Pubs
involved_in Rho protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
acts_upstream_of_or_within Rho protein signal transduction ISO
Inferred from Sequence Orthology
more info
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
located_in cytosol ISO
Inferred from Sequence Orthology
more info
located_in membrane IEA
Inferred from Electronic Annotation
more info
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info

General protein information

Preferred Names
alpha-catenin related protein
catenin (cadherin associated protein), alpha-like 1
catenin alpha-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018761.3NP_061231.3  alpha-catulin

    See identical proteins and their annotated locations for NP_061231.3

    Status: VALIDATED

    Source sequence(s)
    AW536536, BC050070, BG064548, CF896873, CJ094037, CK794820
    Consensus CDS
    O88327, Q810J3
    ENSMUSP00000036487.9, ENSMUST00000045142.15
    Conserved Domains (1) summary
    Vinculin; Vinculin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000070.7 Reference GRCm39 C57BL/6J

    56810935..56865370 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320319.3XP_017175808.1  alpha-catulin isoform X1

    Conserved Domains (1) summary
    Vinculin; Vinculin family