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CYTL1 cytokine like 1 [ Homo sapiens (human) ]

Gene ID: 54360, updated on 27-Nov-2024

Summary

Official Symbol
CYTL1provided by HGNC
Official Full Name
cytokine like 1provided by HGNC
Primary source
HGNC:HGNC:24435
See related
Ensembl:ENSG00000170891 MIM:607930; AllianceGenome:HGNC:24435
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C17; C4orf4
Summary
C17 is a cytokine-like protein specifically expressed in bone marrow and cord blood mononuclear cells that bear the CD34 (MIM 142230) surface marker (Liu et al., 2000 [PubMed 10857752]).[supplied by OMIM, Mar 2008]
Expression
Biased expression in placenta (RPKM 17.2), urinary bladder (RPKM 5.8) and 11 other tissues See more
Orthologs
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Genomic context

See CYTL1 in Genome Data Viewer
Location:
4p16.2
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (5014586..5019458, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (4984228..4989105, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (5016313..5021185, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928306 Neighboring gene uncharacterized LOC107986218 Neighboring gene RN7SK pseudogene 113 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21235 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21236 Neighboring gene uncharacterized LOC107986256 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:5044739-5045239 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:5053909-5054447 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21237 Neighboring gene serine/threonine kinase 32B Neighboring gene Sharpr-MPRA regulatory region 6927 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:5135748-5136346 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:5155881-5156382 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:5167073-5168272 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr4:5200564-5201064 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:5206884-5207384 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:5207385-5207885 Neighboring gene Sharpr-MPRA regulatory region 9083 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:5367115-5368314 Neighboring gene RN7SK pseudogene 275

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
cytokine-like protein 1
Names
cytokine-like protein C17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018659.3NP_061129.1  cytokine-like protein 1 precursor

    See identical proteins and their annotated locations for NP_061129.1

    Status: VALIDATED

    Source sequence(s)
    AC108139
    Consensus CDS
    CCDS3379.1
    UniProtKB/Swiss-Prot
    Q9NRR1
    Related
    ENSP00000303550.4, ENST00000307746.9
    Conserved Domains (1) summary
    pfam15153
    Location:21130
    CYTL1; Cytokine-like protein 1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    5014586..5019458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008299.2XP_016863788.1  cytokine-like protein 1 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    4984228..4989105 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054350197.1XP_054206172.1  cytokine-like protein 1 isoform X1