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camkk1a calcium/calmodulin-dependent protein kinase kinase 1, alpha a [ Danio rerio (zebrafish) ]

Gene ID: 541526, updated on 9-Apr-2018
Official Symbol
camkk1aprovided by ZNC
Official Full Name
calcium/calmodulin-dependent protein kinase kinase 1, alpha aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050327-62
See related
Ensembl:ENSDARG00000035452 Vega:OTTDARG00000017902
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
camkk1; zgc:113440
Orthologs
Location:
chromosome: 5
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (31283216..31436779)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (30682998..30833268)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103911076 Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 Neighboring gene si:dkey-220k22.1 Neighboring gene purinergic receptor P2X, ligand-gated ion channel, 1

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
calmodulin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
calmodulin-dependent protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
peptidyl-threonine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
calcium/calmodulin-dependent protein kinase kinase 1
NP_001014361.1
XP_005171905.1
XP_005171907.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014339.2NP_001014361.1  calcium/calmodulin-dependent protein kinase kinase 1

    See identical proteins and their annotated locations for NP_001014361.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091900
    UniProtKB/TrEMBL
    Q58EH5
    Related
    ENSDARP00000029907.6, ENSDART00000028237.7
    Conserved Domains (2) summary
    smart00220
    Location:56337
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:55338
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    31283216..31436779
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171848.4XP_005171905.1  calcium/calmodulin-dependent protein kinase kinase 1 isoform X1

    Conserved Domains (2) summary
    smart00220
    Location:103384
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14200
    Location:102385
    STKc_CaMKK1; Catalytic domain of the Serine/Threonine kinase, Calmodulin Dependent Protein Kinase Kinase 1
  2. XM_005171850.4XP_005171907.1  calcium/calmodulin-dependent protein kinase kinase 1 isoform X2

    UniProtKB/TrEMBL
    A2BIP2
    Related
    ENSDARP00000122850.1, OTTDARP00000018189, ENSDART00000133743.3
    Conserved Domains (2) summary
    smart00220
    Location:103384
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14200
    Location:102385
    STKc_CaMKK1; Catalytic domain of the Serine/Threonine kinase, Calmodulin Dependent Protein Kinase Kinase 1

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394584.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    9475..83146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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