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LURAP1 leucine rich adaptor protein 1 [ Homo sapiens (human) ]

Gene ID: 541468, updated on 25-Nov-2021

Summary

Official Symbol
LURAP1provided by HGNC
Official Full Name
leucine rich adaptor protein 1provided by HGNC
Primary source
HGNC:HGNC:32327
See related
Ensembl:ENSG00000171357 MIM:616129
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LRP35A; LRAP35a; C1orf190
Expression
Broad expression in thyroid (RPKM 5.9), testis (RPKM 4.8) and 20 other tissues See more
Orthologs
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Genomic context

See LURAP1 in Genome Data Viewer
Location:
1p34.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (46203334..46221256)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (46669006..46686928)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene P3R3URF-PIK3R3 readthrough Neighboring gene phosphoinositide-3-kinase regulatory subunit 3 Neighboring gene uncharacterized LOC101929626 Neighboring gene PIK3R3 upstream open reading frame Neighboring gene tetraspanin 1 Neighboring gene protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) Neighboring gene RAD54 like Neighboring gene leucine rich repeat containing 41 Neighboring gene ubiquinol-cytochrome c reductase hinge protein

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25163

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
leucine rich adaptor protein 1
Names
NF-kappa-B activator C1orf190
leucine repeat adapter protein 35A
leucine repeat adaptor protein 35a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013615.3NP_001013633.1  leucine rich adaptor protein 1

    See identical proteins and their annotated locations for NP_001013633.1

    Status: VALIDATED

    Source sequence(s)
    AI077554, AK057892, BX370151
    Consensus CDS
    CCDS30703.1
    UniProtKB/Swiss-Prot
    Q96LR2
    Related
    ENSP00000361048.3, ENST00000371980.4
    Conserved Domains (1) summary
    pfam14854
    Location:39159
    LURAP; Leucine rich adaptor protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    46203334..46221256
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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