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H2BC12L H2B clustered histone 12 like [ Homo sapiens (human) ]

Gene ID: 54145, updated on 21-Mar-2023

Summary

Official Symbol
H2BC12Lprovided by HGNC
Official Full Name
H2B clustered histone 12 likeprovided by HGNC
Primary source
HGNC:HGNC:4762
See related
Ensembl:ENSG00000234289 AllianceGenome:HGNC:4762
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
H2B/s; H2BFS; H2BS1
Summary
Predicted to enable DNA binding activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to other organism. Located in cytosol; extracellular space; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See H2BC12L in Genome Data Viewer
Location:
21q22.3
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (43565182..43565648)
RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (41920726..41921192)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (44985063..44985529)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene heat shock transcription factor 2 binding protein Neighboring gene Sharpr-MPRA regulatory region 13752 Neighboring gene ribosomal protein L31 pseudogene 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:45003551-45004052 Neighboring gene microRNA 6070

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
histone H2B type F-S
Names
H2B histone family member S
H2B.S histone 1
histone H2B.s
histone protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017445.3NP_059141.1  histone H2B type F-S

    Status: VALIDATED

    Source sequence(s)
    AP001051
    UniProtKB/Swiss-Prot
    Q5R2W0
    Related
    ENSP00000481622.1, ENST00000599962.2
    Conserved Domains (1) summary
    smart00427
    Location:28124
    H2B; Histone H2B

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    43565182..43565648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    41920726..41921192
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_006504.3: Suppressed sequence

    Description
    NG_006504.3: This RefSeq was removed because it is now thought that this locus is a transcribed gene.