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ccnh cyclin H [ Danio rerio (zebrafish) ]

Gene ID: 541325, updated on 5-Jul-2025
Official Symbol
ccnhprovided by ZNC
Official Full Name
cyclin Hprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050320-13
See related
Ensembl:ENSDARG00000007657 AllianceGenome:ZFIN:ZDB-GENE-050320-13
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:114132
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to act upstream of or within DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be part of transcription factor TFIIK complex. Predicted to be active in nucleus. Is expressed in several structures, including immature eye; liver; nervous system; neural tube; and pleuroperitoneal region. Orthologous to human CCNH (cyclin H). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
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See ccnh in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 5 NC_133180.1 (52019818..52031318, complement)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 5 NC_007116.7 (47963940..47975440, complement)

Chromosome 5 - NC_133180.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC141385854 Neighboring gene cytochrome c oxidase subunit 7C Neighboring gene uncharacterized LOC100150296 Neighboring gene uncharacterized LOC137495629 Neighboring gene RAS p21 protein activator (GTPase activating protein) 1a

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in transcription initiation at RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of transcription factor TFIIK complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of transcription factor TFIIK complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
cyclin-H

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013453.1NP_001013471.1  cyclin-H

    See identical proteins and their annotated locations for NP_001013471.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091559
    UniProtKB/TrEMBL
    Q5BJA4
    Related
    ENSDARP00000004735.4, ENSDART00000007057.5
    Conserved Domains (3) summary
    TIGR00569
    Location:2302
    ccl1; cyclin ccl1
    smart00385
    Location:62152
    CYCLIN; domain present in cyclins, TFIIB and Retinoblastoma
    pfam16899
    Location:162262
    Cyclin_C_2; Cyclin C-terminal domain

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133180.1 Reference GRCz12tu Primary Assembly

    Range
    52019818..52031318 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_073950320.1XP_073806421.1  cyclin-H isoform X2

    UniProtKB/TrEMBL
    A0A8M2BCT1, A2BGI0
  2. XM_005165512.6XP_005165569.1  cyclin-H isoform X2

    UniProtKB/TrEMBL
    A0A8M2BCT1, A2BGI0
    Conserved Domains (3) summary
    TIGR00569
    Location:2302
    ccl1; cyclin ccl1
    smart00385
    Location:62152
    CYCLIN; domain present in cyclins, TFIIB and Retinoblastoma
    pfam16899
    Location:162262
    Cyclin_C_2; Cyclin C-terminal domain
  3. XM_073950319.1XP_073806420.1  cyclin-H isoform X1