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ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase [ Bos taurus (cattle) ]

Gene ID: 540876, updated on 14-Jan-2019

Summary

Official Symbol
ABL1provided by VGNC
Official Full Name
ABL proto-oncogene 1, non-receptor tyrosine kinaseprovided by VGNC
Primary source
VGNC:VGNC:50224
See related
BGD:BT28137; Ensembl:ENSBTAG00000017976
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See ABL1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 11 NC_037338.1 (100989350..101131031)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 11 AC_000168.1 (101011169..101152856)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene PR/SET domain 12 Neighboring gene exosome component 2 Neighboring gene pyroglutamylated RFamide peptide Neighboring gene fibrinogen C domain containing 1 Neighboring gene transfer RNA glycine (anticodon CCC)

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

General protein information

Preferred Names
tyrosine-protein kinase ABL1
Names
Abelson murine leukemia viral (v-abl) oncogene homolog 1
c-abl oncogene 1, non-receptor tyrosine kinase
c-abl oncogene 1, receptor tyrosine kinase
v-abl Abelson murine leukemia viral oncogene homolog 1
NP_001193789.1
XP_024854844.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206860.1NP_001193789.1  tyrosine-protein kinase ABL1

    See identical proteins and their annotated locations for NP_001193789.1

    Status: VALIDATED

    Source sequence(s)
    NKLS02000011
    Related
    ENSBTAP00000058693.1, ENSBTAT00000080797.1
    Conserved Domains (5) summary
    smart00808
    Location:10271151
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:142235
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:84137
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:254516
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    pfam07714
    Location:261512
    Pkinase_Tyr; Protein tyrosine kinase

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    100989350..101131031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024999076.1XP_024854844.1  tyrosine-protein kinase ABL1 isoform X1

    Related
    ENSBTAP00000023920.6, ENSBTAT00000023920.6
    Conserved Domains (5) summary
    smart00808
    Location:10081132
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:123216
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:65118
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:235497
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    cl26464
    Location:6221023
    Atrophin-1; Atrophin-1 family
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