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MBD1 methyl-CpG binding domain protein 1 [ Bos taurus (domestic cattle) ]

Gene ID: 540558, updated on 5-Sep-2025
Official Symbol
MBD1provided by VGNC
Official Full Name
methyl-CpG binding domain protein 1provided by VGNC
Primary source
VGNC:VGNC:31273
See related
BGD:BT22679; EnsemblRapid:ENSBTAG00070025302
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See MBD1 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (49898769..49915949, complement)

Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene myosin VB Neighboring gene cofilin-1-like Neighboring gene cilia and flagella associated protein 53 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene CXXC finger protein 1 Neighboring gene spindle and kinetochore associated complex subunit 1

Genomic Sequence:
NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Unexpected cross-species contamination in genome sequencing projects. Merchant S, et al. PeerJ, 2014. PMID 25426337, Free PMC Article
  2. The genome sequence of taurine cattle: a window to ruminant biology and evolution. Bovine Genome Sequencing and Analysis Consortium, et al. Science, 2009 Apr 24. PMID 19390049, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC133916

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables methyl-CpG binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA methylation-dependent constitutive heterochromatin formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
methyl-CpG-binding domain protein 1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001046481.2 → NP_001039946.1  methyl-CpG-binding domain protein 1

    See identical proteins and their annotated locations for NP_001039946.1

    Status: PROVISIONAL

    Source sequence(s)
    BC112458
    UniProtKB/TrEMBL
    A0A3Q1MW55, Q2KIY8
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:357 → 403
    zf-CXXC; CXXC zinc finger domain
    cl26386
    Location:413 → 594
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    49898769..49915949 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059880972.1 → XP_059736955.1  methyl-CpG-binding domain protein 1 isoform X30

    UniProtKB/TrEMBL
    A0A3Q1LIQ1

  2. XM_010818929.3 → XP_010817231.1  methyl-CpG-binding domain protein 1 isoform X27

    UniProtKB/TrEMBL
    A0A3Q1LIQ1, A0AAA9SIL1
    Related
    ENSBTAP00070034278.1, ENSBTAT00070057543.1
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:309 → 355
    zf-CXXC; CXXC zinc finger domain
    cl27975
    Location:363 → 571
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  3. XM_005224260.4 → XP_005224317.1  methyl-CpG-binding domain protein 1 isoform X34

    UniProtKB/TrEMBL
    A0A3Q1LIQ1
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:309 → 355
    zf-CXXC; CXXC zinc finger domain
    cl27975
    Location:363 → 494
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  4. XM_059880969.1 → XP_059736952.1  methyl-CpG-binding domain protein 1 isoform X24

    UniProtKB/TrEMBL
    A0A3Q1LIQ1

  5. XM_059880971.1 → XP_059736954.1  methyl-CpG-binding domain protein 1 isoform X29

    UniProtKB/TrEMBL
    A0A3Q1LIQ1

  6. XM_024984378.2 → XP_024840146.1  methyl-CpG-binding domain protein 1 isoform X26

    UniProtKB/TrEMBL
    A0A3Q1MW55
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331 → 377
    zf-CXXC; CXXC zinc finger domain
    cl26386
    Location:387 → 556
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  7. XM_059880963.1 → XP_059736946.1  methyl-CpG-binding domain protein 1 isoform X16

    UniProtKB/TrEMBL
    A0A3Q1MW55

  8. XM_059880950.1 → XP_059736933.1  methyl-CpG-binding domain protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MW55

  9. XM_024984376.2 → XP_024840144.1  methyl-CpG-binding domain protein 1 isoform X21

    UniProtKB/TrEMBL
    A0A3Q1MW55
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331 → 377
    zf-CXXC; CXXC zinc finger domain
    cl26386
    Location:387 → 568
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  10. XM_010818930.3 → XP_010817232.1  methyl-CpG-binding domain protein 1 isoform X31

    UniProtKB/TrEMBL
    A0A3Q1MW55
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:332 → 378
    zf-CXXC; CXXC zinc finger domain
    cl27975
    Location:386 → 517
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  11. XM_059880965.1 → XP_059736948.1  methyl-CpG-binding domain protein 1 isoform X18

    UniProtKB/TrEMBL
    A0A3Q1MW55

  12. XM_010818931.3 → XP_010817233.1  methyl-CpG-binding domain protein 1 isoform X33

    UniProtKB/TrEMBL
    A0A3Q1MW55
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:332 → 378
    zf-CXXC; CXXC zinc finger domain
    cl27975
    Location:386 → 517
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  13. XM_059880967.1 → XP_059736950.1  methyl-CpG-binding domain protein 1 isoform X22

    UniProtKB/TrEMBL
    A0A3Q1MW55

  14. XM_059880951.1 → XP_059736934.1  methyl-CpG-binding domain protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A3Q1MW55

  15. XM_024984377.2 → XP_024840145.1  methyl-CpG-binding domain protein 1 isoform X25

    UniProtKB/TrEMBL
    A0A3Q1MW55
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:332 → 378
    zf-CXXC; CXXC zinc finger domain
    cl26386
    Location:388 → 557
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  16. XM_059880959.1 → XP_059736942.1  methyl-CpG-binding domain protein 1 isoform X12

    UniProtKB/TrEMBL
    A0A3Q1MW55
    Related
    ENSBTAP00070034287.1, ENSBTAT00070057559.1

  17. XM_059880962.1 → XP_059736945.1  methyl-CpG-binding domain protein 1 isoform X15

    UniProtKB/TrEMBL
    A0A3Q1MW55

  18. XM_005224252.4 → XP_005224309.1  methyl-CpG-binding domain protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MW55
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:332 → 378
    zf-CXXC; CXXC zinc finger domain
    cl26386
    Location:388 → 569
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  19. XM_005224257.4 → XP_005224314.1  methyl-CpG-binding domain protein 1 isoform X20

    UniProtKB/TrEMBL
    A0A3Q1MW55
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:332 → 378
    zf-CXXC; CXXC zinc finger domain
    cl26386
    Location:388 → 569
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  20. XM_059880964.1 → XP_059736947.1  methyl-CpG-binding domain protein 1 isoform X17

    UniProtKB/TrEMBL
    A0A3Q1MW55

  21. XM_059880973.1 → XP_059736956.1  methyl-CpG-binding domain protein 1 isoform X32

    UniProtKB/TrEMBL
    A0A3Q1LIQ1

  22. XM_059880949.1 → XP_059736932.1  methyl-CpG-binding domain protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1MW55

  23. XM_059880966.1 → XP_059736949.1  methyl-CpG-binding domain protein 1 isoform X19

    UniProtKB/TrEMBL
    A0A3Q1LIQ1

  24. XM_059880961.1 → XP_059736944.1  methyl-CpG-binding domain protein 1 isoform X14

    UniProtKB/TrEMBL
    A0A3Q1MW55

  25. XM_059880957.1 → XP_059736940.1  methyl-CpG-binding domain protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A3Q1MW55

  26. XM_059880968.1 → XP_059736951.1  methyl-CpG-binding domain protein 1 isoform X23

    UniProtKB/TrEMBL
    A0A3Q1MW55

  27. XM_059880953.1 → XP_059736936.1  methyl-CpG-binding domain protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A3Q1MW55

  28. XM_059880970.1 → XP_059736953.1  methyl-CpG-binding domain protein 1 isoform X28

    UniProtKB/TrEMBL
    A0A3Q1MW55

  29. XM_059880958.1 → XP_059736941.1  methyl-CpG-binding domain protein 1 isoform X11

    UniProtKB/TrEMBL
    A0A3Q1MW55

  30. XM_024984375.2 → XP_024840143.1  methyl-CpG-binding domain protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1MW55
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:357 → 403
    zf-CXXC; CXXC zinc finger domain
    cl26386
    Location:413 → 582
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  31. XM_059880960.1 → XP_059736943.1  methyl-CpG-binding domain protein 1 isoform X13

    UniProtKB/TrEMBL
    A0A3Q1MW55

  32. XM_059880952.1 → XP_059736935.1  methyl-CpG-binding domain protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A3Q1MW55

  33. XM_024984374.2 → XP_024840142.1  methyl-CpG-binding domain protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MRI0, A0A3Q1MW55
    Related
    ENSBTAP00070034269.1, ENSBTAT00070057527.1
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:357 → 403
    zf-CXXC; CXXC zinc finger domain
    cl26386
    Location:413 → 594
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  34. XM_005224253.4 → XP_005224310.1  methyl-CpG-binding domain protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A3Q1LUL8, A0A3Q1MW55
    Conserved Domains (4) summary
    smart00391
    Location:3 → 76
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:357 → 403
    zf-CXXC; CXXC zinc finger domain
    cl26386
    Location:413 → 594
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28054
    Location:28 → 151
    Pox_Ag35; Pox virus Ag35 surface protein

  35. XM_059880956.1 → XP_059736939.1  methyl-CpG-binding domain protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A3Q1LUL8, A0A3Q1MW55
    Related
    ENSBTAP00070034251.1, ENSBTAT00070057486.1

  36. XM_059880955.1 → XP_059736938.1  methyl-CpG-binding domain protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A3Q1LUL8, A0A3Q1MW55

  37. XM_059880954.1 → XP_059736937.1  methyl-CpG-binding domain protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A3Q1LUL8, A0A3Q1MW55
Nucleotide Protein Strain
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